Results 41 to 50 of about 580,743 (343)
Caspase-1 Is an Apical Caspase Leading to Caspase-3 Cleavage in the AIM2 Inflammasome Response, Independent of Caspase-8 [PDF]
Journal of Molecular Biology, 2018 Canonical inflammasomes are multiprotein complexes that can activate both caspase-1 and caspase-8. Caspase-1 drives rapid lysis of cells by pyroptosis and maturation of interleukin (IL)-1β and IL-18. In caspase-1-deficient cells, inflammasome formation still leads to caspase-3 activation and slower apoptotic death, dependent on caspase-8 as an apical ...
Sagulenko, Vitaliya +4 more
openaire +4 more sources
Analysis Expression of ZIP1 and Caspase-3 Protein in Adenocarsinoma of the Prostate [PDF]
, 2016 Background: Carcinogenesis of adenocarcinoma of the prostate occurs due to dysregulation of zinc level within the cells. Intracellular zinc molecules influx is regulated by a transporter protein ZIP1, whose non-presence is predicted to inhibit apoptosis,
Kodariah, R. (Ria) +2 more
core +3 more sources
Molecules, 2014 Cervical cancer is the second most common female carcinoma. Current therapies are often unsatisfactory, especially for advanced stage patients. The aim of this study was to explore the effects of tatariside G (TG) on apoptosis in human cervical cancer ...
Yuan Li +7 more
doaj +1 more source
Impact of L-carnitine and selenium treatment on testicular apoptosis in rats exposed to 2.45 GHz microwave energy [PDF]
, 2015 Objective: It has been suggested that electromagnetic radiation (EMR) by wireless devices (2.45 GHz) induces testicular apoptosis. We investigated if supplemental selenium (Se) and L-carnitine may reduce this adverse effect.
Comlekci, S. +5 more
core +1 more source
Ceramide-Induced Cell Death Depends on Calcium and Caspase-Like Activity in Rice
Frontiers in Plant Science, 2020 Ceramide sphingolipids are major components of membranes. C2 and C6 ceramides induce programmed cell death (PCD) in animals and plants, and we previously showed that C2 and C6 ceramides induce PCD in rice (Oryza sativa) protoplasts.
Quan-Fang Zhang +7 more
doaj +1 more source
Pyroptosis: A Developing Foreland of Ovarian Cancer Treatment
Frontiers in Oncology, 2022 Ovarian cancer (OVCA) has the second highest mortality among all gynecological cancers worldwide due to its complexity and difficulty in early-stage diagnosis and a lack of targeted therapy.
Tianyi Liu +12 more
doaj +1 more source
, 2018 In this issue of JEM, Boucher et al. (https://doi.org/10.1084/jem.20172222) report isolation of active caspase-1 from macrophages after inflammasome activation.
Sandstrom, Andrew, VANCE, Russell E.
core +1 more source
Striking a balance: Modulation of host cell death pathways by Legionella pneumophila
Frontiers in Cellular and Infection Microbiology, 2011 Programmed cell death is considered the ultimate solution for the host to eliminate infected cells, leading to the abolishment of the niche for microbial replication and the ablation of infection.
Zhao-Qing eLuo
doaj +1 more source
Asian Pacific Journal of Tropical Biomedicine, 2018 Objective: To evaluate the anticancer activity of crude acetone and water leaf extracts of Tulbaghia violacea on a human oral cancer cell line (KB). Methods: The antioxidant activity of the leaf extracts was evaluated by using the DPPH assay while the ...
Samkeliso Takaidza +5 more
doaj +1 more source
Cellular plasticity, caspases and autophagy; that which does not kill us, well, makes us different [PDF]
Open Biology, 2018 The ability to regenerate is a fundamental requirement for tissue homeostasis. Regeneration draws on three sources of cells. First and best-studied are dedicated stem/progenitor cells.
Tin Tin Su
doaj +1 more source