Results 81 to 90 of about 333,383 (311)
Molecules, 2018 The natural product 23-hydroxyursolic acid (23-HUA) is a derivative of ursolic acid, which is known to induce cancer cell apoptosis. However, apoptotic effects and mechanisms of 23-HUA have not been well characterized yet.
Jong-Heon Won +9 more
doaj +1 more source
Monte Carlo study elucidates the type 1/type 2 choice in apoptotic death signaling in normal and cancer cells [PDF]
Cells 2013 2:361-392, 2013 Apoptotic cell death is coordinated through two distinct (type 1 and type 2) intracellular signaling pathways. How the type 1/type 2 choice is made remains a fundamental problem in the biology of apoptosis and has implications for apoptosis related diseases and therapy.
arxiv
Advanced Functional Materials, EarlyView.Designer DNA Architecture‐templated Drug Conjugates (DDA‐DCs) are comprised of a DNA nanomaterial decorated with multiple drug‐loaded DNA aptamers. DDA‐DCs use a combination of multiple aptamer types, each recognizing a different membrane protein to achieve precise targeting of cancer cells.
Abhisek Dwivedy +19 more
wiley +1 more source
International Journal of Nanomedicine, 2020 Badr E El Bialy, 1 Ragaa A Hamouda, 2, 3 Mabrouk A Abd Eldaim, 4 Salah S El Ballal, 5 Hanim S Heikal, 6 Hanem K Khalifa, 7 Wael N Hozzein 8, 9 1Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, University of Sadat City ...
El Bialy BE +6 more
doaj
Modeling the effects of HIV-1 virions and proteins on Fas-induced apoptosis of infected cells [PDF]
arXiv, 2007 We report a first in modeling and simulation of the effects of the HIV proteins on the (caspase dependent) apoptotic pathway in infected cells. This work is novel and is an extension on the recent reports and clarifications on the FAS apoptotic pathway from the literature.
arxiv
H2O2‐Generating Advanced Nanomaterials for Cancer Treatment
Advanced Functional Materials, EarlyView.H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie +8 more
wiley +1 more source
Non-autonomous consequences of cell death and other perks of being metazoan
AIMS Genetics, 2015 Drosophila melanogaster remains a foremost genetic model to study basic cell biological processes in the context of multi-cellular development. In such context, the behavior of one cell can influence another.
Tin Tin Su
doaj +1 more source
Density-based modeling and identification of biochemical networks in cell populations [PDF]
arXiv, 2010 In many biological processes heterogeneity within cell populations is an important issue. In this work we consider populations where the behavior of every single cell can be described by a system of ordinary differential equations. Heterogeneity among individual cells is accounted for by differences in parameter values and initial conditions.
arxiv
Advanced Healthcare Materials, EarlyView.This study developed a biomimetic scaffold incorporating PDRN and melatonin to restore ovarian function in chemotherapy‐induced premature ovarian insufficiency, enhancing cell survival, folliculogenesis, and hormone normalization, while improving fertility rates and offspring in a mouse model, offering a promising strategy for ovarian function ...
Da‐Seul Kim +8 more
wiley +1 more source
The Journal of Cell Biology, 2004 Stress in the endoplasmic reticulum (ER)—caused by anything from ischemia to expression of mutant proteins—triggers several responses. Cells slow translation, produce more chaperones, degrade more unfolded proteins, and as a last resort, induce apoptosis. Hitomi et al. (page 347) identify caspase-4 as a critical component of the pathway leading from ER
openaire +2 more sources