Results 101 to 110 of about 628,785 (360)
Caspase-3 activity increases following QLT-0276 treatment in paired females. [PDF]
, 2017 Result of the caspase-3 activity assay showing that compared to a DMSO-treated control (left) the activity of caspase-3 of S. mansoni increased significantly (p = 0.01) in paired females treated with 100 μM QLT-0276 (right) as determined ...
Steffen Hahnel (437327) +5 more
core +1 more source
Caspase-8 content in SNU-1 cells. [PDF]
, 2021 Increases in intracellular Caspase-8 compared to blank (untreated) SNU-1 cells upon treatment with 50–5000 nm sized aminated, carboxylated and NF particles for 4 h. Data compared with respect to surface functionalization (A) or particle size (B).
Amrita Banerjee (382658) +2 more
core +1 more source
Garcinol A Novel Inhibitor of Platelet Activation and Apoptosis
Toxins, 2019 Garcinol, an anti-inflammatory and anti-carcinogenic polyisoprenylated benzophenone isolated from Garcinia plants, stimulates tumor cell apoptosis and suicidal erythrocyte death, but supports the survival of hepatocytes and neurons.
Hang Cao +8 more
doaj +1 more source
Science Advances, 2020 Caspase-8–dependent GSDMD activation promotes antibacterial defense; however, this pathway can also mediate TNF shock in vivo. Gasdermin D (GSDMD) is a pore-forming protein that promotes pyroptosis and release of proinflammatory cytokines. Recent studies
B. Demarco +13 more
semanticscholar +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Caspase-3 immunohistochemical staining of kidney section of rats. [PDF]
, 2016 Kidney sections of normal rats (a) showing no immune-reactive cells, PDC-treated group (b) showing Diffuse intensely stained immune-reactive cells, PDC-Lf (200 mg/kg) treated rats (c) showing few number of faintly stained immune-reactive cells, and PDC ...
Azza Hassan (678637) +3 more
core +1 more source
Molecules, 2018 Two tetrahydrofurofurano lignans (1 and 2), four phenylpropanoids (3–6), and two alkamides (7 and 8) were isolated from the EtOAc-soluble fraction of the roots of Asarum sieboldii. The chemical structures of the isolates were identified by analysis
Miran Jeong +4 more
doaj +1 more source
Polyphenols of Frangula alnus and Peganum harmala Leaves and Associated Biological Activities
Plants, 2020 Frangula alnus and Peganum harmala populations growing in Saudi Arabia might be rich sources of natural compounds with important biological activities. A high performance liquid chromatography diode array revealed several polyphenols in the leaf extracts
Hosam O. Elansary +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Caspase-independent role of Apaf1 in T cell activation. [PDF]
, 2018 LN cells from immunized Apaf1f/f-OTII or Lck-Cre-Apaf1f/f -OTII mice were stimulated with indicated doses of OVA or anti-CD3ε antibody in the presence or absence of z-VAD-fmk (z-VAD) for 48 hours.
Yasunobu Miyake (522605) +5 more
core +1 more source