Results 111 to 120 of about 422,774 (309)
Sepsis is generally considered as a severe condition of inflammation that leads to lymphocyte apoptosis and multiple organ dysfunction. Hydroxysafflor yellow A (HSYA) exerts anti-inflammatory and anti-apoptotic effects in infectious diseases.
Jinping Wang +9 more
doaj +1 more source
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang +13 more
wiley +1 more source
Apoptosis is obligatory to development and in maintaining the vital balance between cell growth and death. Commitment to apoptosis involves a proteolytic cascade by a family of cysteine proteases named caspases.
Feeney, Brett
core
Caspase-3 activity increases following QLT-0276 treatment in paired females.
Result of the caspase-3 activity assay showing that compared to a DMSO-treated control (left) the activity of caspase-3 of S. mansoni increased significantly (p = 0.01) in paired females treated with 100 μM QLT-0276 (right) as determined ...
Steffen Hahnel (437327) +5 more
core +1 more source
Caspase-8 content in SNU-1 cells.
Increases in intracellular Caspase-8 compared to blank (untreated) SNU-1 cells upon treatment with 50–5000 nm sized aminated, carboxylated and NF particles for 4 h. Data compared with respect to surface functionalization (A) or particle size (B).
Amrita Banerjee (382658) +2 more
core +1 more source
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova +4 more
wiley +1 more source
Caspase-3 immunohistochemical staining of kidney section of rats.
Kidney sections of normal rats (a) showing no immune-reactive cells, PDC-treated group (b) showing Diffuse intensely stained immune-reactive cells, PDC-Lf (200 mg/kg) treated rats (c) showing few number of faintly stained immune-reactive cells, and PDC ...
Azza Hassan (678637) +3 more
core +1 more source
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu +12 more
wiley +1 more source
Caspase-independent role of Apaf1 in T cell activation.
LN cells from immunized Apaf1f/f-OTII or Lck-Cre-Apaf1f/f -OTII mice were stimulated with indicated doses of OVA or anti-CD3ε antibody in the presence or absence of z-VAD-fmk (z-VAD) for 48 hours.
Yasunobu Miyake (522605) +5 more
core +1 more source
Marlyn P Langford, Alexandra R Sebren, Maxwell A Burch, Thomas B Redens Department of Ophthalmology, Louisiana State University Health Sciences Center, Shreveport, LA 71130, USACorrespondence: Marlyn P LangfordDepartment of Ophthalmology, Louisiana State
Langford MP +3 more
doaj

