Results 71 to 80 of about 422,774 (309)

Caspase-Dependent and Caspase-Independent Pathways Are Involved in Cadmium-Induced Apoptosis in Primary Rat Proximal Tubular Cell Culture.

open access: yes, 2016
We designed this study to investigate whether cadmium induces caspase-independent apoptosis and to investigate the relationship between the caspase-dependent and caspase-independent apoptotic pathways.
Xuezhong Liu   +23 more
core   +1 more source

Caspase-3 content in SNU-1 cells.

open access: yes, 2021
Increase in intracellular Caspase-3 compared to blank (untreated) SNU-1 cells upon treatment with 50–5000 nm sized aminated, carboxylated and NF particles for 4 h. Data compared with respect to surface functionalization (A) or particle size (B). All data
Amrita Banerjee (382658)   +2 more
core   +1 more source

(−)-Asarinin from the Roots of Asarum sieboldii Induces Apoptotic Cell Death via Caspase Activation in Human Ovarian Cancer Cells

open access: yesMolecules, 2018
Two tetrahydrofurofurano lignans (1 and 2), four phenylpropanoids (3–6), and two alkamides (7 and 8) were isolated from the EtOAc-soluble fraction of the roots of Asarum sieboldii. The chemical structures of the isolates were identified by analysis
Miran Jeong   +4 more
doaj   +1 more source

Polyphenols of Frangula alnus and Peganum harmala Leaves and Associated Biological Activities

open access: yesPlants, 2020
Frangula alnus and Peganum harmala populations growing in Saudi Arabia might be rich sources of natural compounds with important biological activities. A high performance liquid chromatography diode array revealed several polyphenols in the leaf extracts
Hosam O. Elansary   +5 more
doaj   +1 more source

Caspase Activation by Anticancer Drugs:  The Caspase Storm

open access: yesMolecular Pharmaceutics, 2007
This study measures the time-dependence of cellular caspase activation by anticancer drugs and compares it with that of cellular respiration. Intracellular caspase activation and cellular respiration were measured during continuous exposure of Jurkat, HL-60, and HL-60/MX2 (deficient in topoisomerase-II) cells to dactinomycin, doxorubicin, and the ...
Tao, Zhimin   +3 more
openaire   +2 more sources

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Caspase-4 and -5 expression in HIOs and inhibition.

open access: yes, 2022
A. Western blot measuring Caspase-4 levels in HIO lysates microinjected with PBS or STM. Blot was probed for Actin as a loading control. B. Western blot measuring Caspase-5 levels in HIO lysates that were microinjected with PBS or STM. Lysates from human
David R. Hill (2330602)   +13 more
core   +1 more source

Senescence and Apoptosis During in vitro Embryo Development in a Bovine Model

open access: yesFrontiers in Cell and Developmental Biology, 2020
According to the World Health Organization, infertility affects up to 14% of couples under reproductive age, leading to an exponential rise in the use of assisted reproduction as a route for conceiving a baby.
Priscila Ramos-Ibeas   +5 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells

open access: yes, 2012
For a long time necrosis was thought to be an uncontrolled process but evidences recently have revealed that necrosis can also occur in a regulated manner.
Gabor Barna (146087)   +20 more
core   +1 more source

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