Results 161 to 170 of about 24,063,457 (338)

RBC Membrane‐Camouflaged Nanosystem‐Mediated Synergistic Drug Combination for Enhanced Anti‐Tumor Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng   +6 more
wiley   +1 more source

Nanocarrier‐Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail   +3 more
wiley   +1 more source

Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang   +6 more
wiley   +1 more source

Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1 [PDF]

open access: green, 1999
Kohji Moriishi   +3 more
openalex   +1 more source

Caspase-1 Engages Full-Length Gasdermin D through Two Distinct Interfaces That Mediate Caspase Recruitment and Substrate Cleavage.

open access: yesImmunity, 2020
Zhonghua Liu   +6 more
semanticscholar   +1 more source

Magnetically Controlled Reversible Photomagnetic Nanoactuators for Dynamic Contrast Enhancement in Optical Coherence Tomography

open access: yesAdvanced Materials, EarlyView.
Photomagnetic nanoactuators with ≈90% scattering efficiency in the second near‐infrared window are demonstrated to exhibit magnetic field‐controlled modulation of optical scattering and optical coherence tomography signals. These nanoactuators are reversibly assembled and disassembled under the external magnetic field modulation, enabling enhanced ...
Myeongsoo Kim   +5 more
wiley   +1 more source

Identification of caspases that cleave presenilin‐1 and presenilin‐2 [PDF]

open access: green, 1999
Marc Van de Craen   +10 more
openalex   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

open access: yesAdvanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy