Results 161 to 170 of about 24,063,457 (338)
An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng+6 more
wiley +1 more source
Caspase-1 is activated in neural cells and tissue with amyotrophic lateral sclerosis-associated mutations in copper-zinc superoxide dismutase [PDF]
Piera Pasinelli+4 more
openalex +1 more source
This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail+3 more
wiley +1 more source
Interleukin-18 Regulation of Interferon γ Production and Cell Proliferation as Shown in Interleukin-1β–Converting Enzyme (Caspase-1)-Deficient Mice [PDF]
Giamila Fantuzzi+4 more
openalex +1 more source
Impact of Nanoparticle Stiffness on Endosomal Escape and Signaling Pathways in Cytosolic Delivery
Nanoparticle (NP) stiffness affects cellular uptake, but its impact on intracellular distribution remains unclear. This study synthesizes silica nanocapsules with varying stiffness, inspired by viral mechanisms, and applies assays to measure cellular uptake and escape efficiency.
Yali Zhang+6 more
wiley +1 more source
Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1 [PDF]
Kohji Moriishi+3 more
openalex +1 more source
Photomagnetic nanoactuators with ≈90% scattering efficiency in the second near‐infrared window are demonstrated to exhibit magnetic field‐controlled modulation of optical scattering and optical coherence tomography signals. These nanoactuators are reversibly assembled and disassembled under the external magnetic field modulation, enabling enhanced ...
Myeongsoo Kim+5 more
wiley +1 more source
Identification of caspases that cleave presenilin‐1 and presenilin‐2 [PDF]
Marc Van de Craen+10 more
openalex +1 more source
DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding+5 more
wiley +1 more source