Results 111 to 120 of about 17,150,662 (399)
Bacterial secreted effectors and caspase‐3 interactions [PDF]
Cellular Microbiology, 2014 Apoptosis is a critical process that intrinsically links organism survival to its ability to induce controlled death. Thus, functional apoptosis allows organisms to remove perceived threats to their survival by targeting those cells that it determines pose a direct risk.
Wall, Daniel M., McCormick, Beth A.
openaire +4 more sources
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
PLoS ONE, 2017 Apoptosis plays a dual role in cancer development and malignancy. The role of apoptosis-related caspases in cancer remains controversial, particularly in oral tongue squamous cell carcinoma (OTSCC).
Pei-Feng Liu +11 more
semanticscholar +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
eLife, 2016 Caspase-3 carries out the executioner phase of apoptosis, however under special circumstances, cells can survive its activity. To document systematically where and when cells survive caspase-3 activation in vivo, we designed a system, CasExpress, which ...
Austin Xun Ding +5 more
semanticscholar +1 more source
Controlling TRAIL-mediated caspase-3 activation [PDF]
Leukemia, 2004 This commentary is addressed at the paper by Dr Jie and his co-workers in the current issue of Leukemia (‘Differential involvement of Bax and Bak in TRAIL-mediated apoptosis of leukemic T cells’). In this paper, the authors show the preferential use of Bax over Bak for the induction of mitochondrial apoptotic events in leukemic cell exposed to TRAIL 1.
Micheau, Olivier, Mérino, Delphine
openaire +4 more sources
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2019 Background and Objectives: Various studies have shown that sex steroids affect cancer cells at cellular and molecular level. In this study, the anti-proliferation effects of testosterone, was investigated on gastric cancer cell line (AGS) and activity ...
Neda Amani +4 more
doaj
Majalah Kedokteran Bandung, 2013 The presence of Plasmodium in erythrocytes will induce immune responses, including the production of free radicals which can lead to lung tissue cells damage.
Loeki Enggar Fitri +4 more
doaj +1 more source
Product Ranks of the $3\times 3$ Determinant and Permanent [PDF]
Canad. Math. Bull. 59 (2016), no. 2 pp. 311-319, 2015 We show that the product rank of the $3\times 3$ determinant is $5$, and the product rank of the $3\times 3$ permanent is $4$. As a corollary, we obtain that the tensor ranks of the $3 \times 3$ determinant and permanent are $5$ and $4$, respectively. We show moreover that the border product rank of the $n \times n$ permanent is larger than $n$ for any
arxiv +1 more source
Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes. [PDF]
, 2015 Bucillamine is used for the treatment of rheumatoid arthritis. This study investigated the protective effects of bucillamine against cisplatin-induced damage in auditory cells, the organ of Corti from postnatal rats (P2) and adult Balb/C mice.
Choe, Seong-Kyu +11 more
core +2 more sources