Results 181 to 190 of about 390,973 (308)

Chicken caspase-3 promotes IBDV replication via the cleavage of IRF7. [PDF]

Front Microbiol
Chen Y, Chen J, Xiang Y, Wei S, Zhao M, Fu K, Li Y, Chen H, Wei P, He X.   +9 more
europepmc   +1 more source

CD44‐Targeting Hydroxyapatite Nanoparticles (HAP) Induce Mitochondrial Dysfunction‐Driven PANoptosis and Immunogenic Cell Death (ICD) via Ca Overload in Colorectal Cancer

Advanced Science, EarlyView.
ABSTRACT Colorectal cancer (CRC) remains therapeutically challenging due to high metastasis, recurrence, and immunotherapy resistance driven by tumor microenvironment‐mediated immune evasion. Immunogenic cell death (ICD) offers a promising strategy to reshape the immune microenvironment, yet existing ICD inducers suffer from poor targeting efficiency ...
Yao Xiao, Yuxuan Yang, Haosen Qiu, Jia Yang, Hao Liang, Zhaojun Jiang, Xiao Tong, Yongying Li, Qunfeng Huang, Jiaming Wu, Tian Lin, Jiang Yu, Min Liang   +12 more
wiley   +1 more source

Caspase-3/7 deficiency results in enhanced intestinal inflammation and reduced tumorigenesis. [PDF]

Sci Adv
Xie W, Wyckaert L, Vadi M, Verstraeten B, Divert T, Haerinck J, De Rycke R, Baeke F, Lamkanfi M, Berx G, Wahida A, Vandenabeele P.   +11 more
europepmc   +1 more source

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

Comparison of salivary caspase-3 biomarker in peri-implantitis among type 2 diabetic patients. [PDF]

Bioinformation
Kiran M, Gupta AK, Bala D, Vynat GP, Kumar KR, S M M, Mohsin SF, Almutairi BM.   +7 more
europepmc   +1 more source

Activated Caspase-3 [PDF]

, 2020
openaire   +1 more source

Brown Adipocyte Sheets Alleviate Myocardial Ischemia–Reperfusion Injury Through NRG4–ErbB4–Dependent Ferroptosis Inhibition

Advanced Science, EarlyView.
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun, Yuting Liu, Jingbo Zhang, Takuji Kawamura, Junjun Li, Li Liu, Shigeru Miyagawa   +6 more
wiley   +1 more source

Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor

, 2011
Berberine, an isoquinoline alkaloid derived from plants, is a traditional medicine for treating bacterial diarrhea and intestinal parasite infections. Although berberine has recently been shown to suppress growth of several tumor cell lines, information ...
Tianhui Hu, Rupesh Chaturvedi, Yan Shi, Hamwei Cao, Fang Yan, Lihong Wang, Liping Liu, Keith Wilson, D. Brent Polk   +8 more
core  

Protective Effects of Oxytocin on Experimental Colitis: Modulation of Cytokines, Oxidative Stress, and Caspase-3 Activity. [PDF]

Medicina (Kaunas)
Aydinli Kazalak B, Yaman S, Ozcelik MF, Senturk GE, Aydinli R, Kaleci B, Uzun H.   +6 more
europepmc   +1 more source

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source