Results 191 to 200 of about 17,150,662 (399)

Peroxynitrite induces apoptosis of HL-60 cells by activation of a caspase-3 family protease [PDF]

, 1998
King-Teh Lin, Jiyan Xue, Marie C. Lin, Eric G. Spokas, Frank F. Sun, Patrick Y.-K. Wong   +5 more
openalex   +1 more source

Profil Ekspresi Caspase-3 Pada Kanker Ovarium Tipe Epitel [PDF]

, 2013
Penelitian ini bertujuan mengetahui profil ekspresi caspase-3 pada kanker ovarium tipe epitel. Rancangan penelitian ini adalah cross-sectional deskriptif. Sampel penelitian adalah pasien kanker ovarium di RSUD Dr.
Budiana, I. N. (I), Budiono, B. (Budiono), Hoesin, F. (Faroek), Suhatno, S. (Suhatno)   +3 more
core  

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Colour-SU(3)-Ginzburg-Landau Effective Potential for Order Parameter with $3 \times 3$ Symmetry II : A Complete Classification of Phase Diagrams [PDF]

arXiv, 2004
Phase structure is studied for a system which has symmetry group SU(3) and is described by SU(3)-${\bf 3 \times 3}$ order parameter. The study is rested on SU(3)-Ginzburg-Landau effective potential constructed as a preliminary.
arxiv  

Temporal relationships between de novo protein synthesis, calpain and caspase 3-like protease activation, and DNA fragmentation during apoptosis in septo-hippocampal cultures [PDF]

, 1998
G. Bruce Pike, Xiurong Zhao, Jennifer K. Newcomb, Kevin Wang, Rand Posmantur, Ronald L. Hayes   +5 more
openalex   +1 more source

Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8+ T Cells Apoptosis with Calcium Overload and Mitochondrial Dysfunction

Advanced Science, EarlyView.
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu, Peng Peng, Changze Wei, Fanhui Meng, Xiaoyao Huang, Peisheng Liu, Siyuan Fan, Xinyue Cai, Meiling Wu, Zilin Xuan, Qing Liu, Xinyu Qiu, Zhenlai Zhu, Hao Guo   +13 more
wiley   +1 more source

The abstract groups (3, 3 | 3, p), their subgroup structure, and their significance for the non-associative finite simple Moufang loops [PDF]

Quasigroups and Related Systems 8 (2001), 97-104, 2007
For most (and possibly all) non-associative finite simple Moufang loops, three generators of order 3 can be chosen so that each two of them generate a group isomorphic to $(3, 3 | 3, p)$. The subgroup structure of $(3, 3 | 3, p)$ depends on the solvability of a certain quadratic congruence, and it is described here in terms of generators.
arxiv  

Caspases‐3 and ‐7 are activated in goniothalamin‐induced apoptosis in human Jurkat T‐cells [PDF]

, 1999
Salmaan H. Inayat‐Hussain, Annuar Bin Osman, Laily B. Din, Abdul Manaf Ali, Roger T. Snowden, Marion MacFarlane, Kelvin Cain   +6 more
openalex   +1 more source

GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy

Advanced Science, EarlyView.
A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang, Runhua Zhou, Chengchao Xu, Lingyun Dai, Rui Hou, Liuhai Zheng, Chunjin Fu, Guangwei Shi, Jingwei Wang, Yang Li, Jinpeng Cen, Xiaolong Xu, Le Yu, Yilei Li, Jigang Wang, Qingfeng Du, Zhijie Li   +16 more
wiley   +1 more source

Caspase-9 swings both ways in the apoptosome

Molecular & Cellular Oncology, 2017
For nearly 2 decades, investigators have debated whether cysteinyl-aspartate-specific protease 9 (caspase-9) is activated within the apoptotic protease-activating factor 1 (Apaf-1) apoptosome through proximity-induced homodimerization or through ...
Chu-Chiao Wu, Shawn B. Bratton
doaj   +1 more source