Results 291 to 300 of about 17,150,662 (399)

Bimetallic Ca/Zn Nanoagonist Remould the Immunosuppressive Hepatocellular Carcinoma Microenvironment Following Incomplete Microwave Ablation via Pyroptosis and the STING Signaling Pathway

Advanced Science, EarlyView.
The multifunctional bimetallic Ca/Zn nanoagonist (PZH/Zn@CaNA) significantly downregulated the JAK2‐STAT3 signaling pathway, which effectively inhibited the proliferation and growth of HCC with incomplete microwave ablation. Furthermore, the released bimetallic ions (Ca2⁺ and Zn2⁺) synergistically enhanced oxidative stress‐mediated cytotoxicity ...
Yuan Ling, Xiayi Liang, Kangning Yan, Guichun Zeng, Xiaoqi Zhu, Jinghang Jiang, Shaolong Lu, Xiaobo Wang, Yuying Zhou, Zhaoshen Li, Wei Mai, Duo Wang, Jie Chen   +12 more
wiley   +1 more source

Caspase 3/GSDME-Mediated Corneal Epithelial Pyroptosis Promotes Dry Eye Disease. [PDF]

Invest Ophthalmol Vis Sci
Wang L, Tian Y, Zhang H, Dong Y, Hua X, Yuan X.   +5 more
europepmc   +1 more source

Ammonia induces apoptosis in gastric chief cell cultures by damaging mitochondria and activating caspase-3

, 2000
Hui Wu, Susan J. Hagen
openalex   +1 more source

Apoptotic signalling cascade in photosensitized human epidermal carcinoma A431 cells: involvement of singlet oxygen, c-Jun N-terminal kinase, caspase-3 and p21-activated kinase 2 [PDF]

, 2000
Wen‐Hsiung Chan, Jau‐Song Yu, Shiaw‐Der Yang   +2 more
openalex   +1 more source

In Vivo Cytosolic Delivery of Biomolecules into Neurons for Super‐Resolution Imaging and Genome Modification

Advanced Science, EarlyView.
The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge, Joseph B. Wekselblatt, Scott Elmore, Bo Wang, Tongtong Wang, Renjinming Dai, Tingting Zhang, Harsh Dave, Mohammadaref Ghaderi, Athul Raj Anilkumar, Bill Wang, Shashank R. Sirsi, Jung‐Mo Ahn, Mikhail G. Shapiro, Yuki Oka, Carlos Lois, Zhenpeng Qin   +16 more
wiley   +1 more source

Expression of Bcl-2 family and caspase-3 activity in human neutrophils by Helicobacter pylori watersoluble surface proteins

, 2000
Joo Sung Kim, Jung Mogg Kim, Hyun Chae Jung, You Sun Kim, Il Ju Choi, In Sung Song, Chung Yong Kim   +6 more
openalex   +1 more source

Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8 [PDF]

, 2000
Henning R. Stennicke, Martin Renatus, Morten Meldal, Guy S. Salvesen   +3 more
openalex   +1 more source

Robust Controlled Degradation of Enzyme Loaded PCL‐Based Fibrous Scaffolds Toward Scarless Skin Tissue Regeneration

Advanced Science, EarlyView.
A novel biodegradable wound dressing (E‐PCLs) based on polycaprolactone (PCL) and an enzyme complex (RHP‐BCL) is developed using a fiber microfluidic electrospinning technique. The dressing achieves complete degradation within 14 days, eliminates microplastic residues, and promotes scar‐free healing (99% in 21 days).
Lingling Fan, Weiliang Dong, Jianqi Lu, Yujia Peng, Bin Xie, Ping Wei, Min Jiang, Su Chen   +7 more
wiley   +1 more source

Memantine abrogates testicular dysfunction induced by risperidone in rats with a potential role of ERK1/2-Nrf2-caspase-3 signaling pathway. [PDF]

Sci Rep
Mohyeldin RH, Sharata EE, Fawzy MA, Attya ME, Welson NN, Rofaeil RR.   +5 more
europepmc   +1 more source

Rapid caspase‐3 activation during apoptosis revealed using fluorescence‐resonance energy transfer

, 2000
Lorraine Tyas, Victoria A. Brophy, Andrew J. Pope, A. Jennifer Rivett, Jeremy M. Tavaré   +4 more
openalex   +1 more source