Results 1 to 10 of about 328,165 (224)

Evaluation of the Potential Diagnostic Utility of the Determination of Selected Caspases—Markers Involved in the Regulation of Apoptosis—In Patients with Ovarian Cancer

open access: yesDiagnostics, 2021
Ovarian cancer remains a major diagnostic and therapeutic problem in modern gynecological oncology. For this reason, research which focuses on the search for new diagnostic markers and the assessment of their possible usefulness in clinical practice is ...
Aleksandra Mielczarek-Palacz   +2 more
doaj   +1 more source

GENETIC POLYMORHISM OF CASPASE 8 AND 9 IN IRAQ

open access: yesThe Iraqi Journal of Agricultural science, 2022
This study examined the potential association between polymorphisms of Caspase 9 −293del (rs4645982) and Caspase8−652 6N ins / del (rs3834129) and the danger of acute and chronic myeloid leukaemia in Iraqi population.
Duaa Abdullah , Reema M. Aloubaidy
doaj   +1 more source

Immunohistochemical analysis of caspase expression in the brains of individuals with obesity or overweight

open access: yesObesity Science & Practice, 2023
Mechanisms underlying the negative effects of obesity on the brain are still unknown. Obesity is associated with oxidative stress in the brain and neuroinflammation that promotes neurodegenerative diseases.
Erick Gómez‐Apo   +4 more
doaj   +1 more source

Serum Interleukin-13 and Caspase 8 are Elevated in Prurigo Nodularis

open access: yesActa Dermato-Venereologica, 2023
is missing (Short communication)
Teresa Ju   +10 more
doaj   +1 more source

Total extract of Abelmoschus manihot L. alleviates uric acid-induced renal tubular epithelial injury via inhibition of caspase-8/caspase-3/NLRP3/GSDME signaling

open access: yesFrontiers in Pharmacology, 2022
Purpose: The incidence of uric acid (UA)-induced kidney injury is increasing owing to the high incidence of hyperuricemia in recent years. The flower of Abelmoschus manihot (Linneus) Medik is a traditional Chinese medicinal herb widely used in the ...
Zhihui Ding   +14 more
doaj   +1 more source

RIPK3 and caspase 8 collaborate to limit herpes simplex encephalitis.

open access: yesPLoS Pathogens, 2022
Invasion of the brain by herpes simplex virus 1 (HSV1) can lead to the development of herpes simplex encephalitis (HSE) that is often associated with significant morbidity and mortality regardless of therapeutic intervention.
Hongyan Guo   +3 more
doaj   +1 more source

The Current Role of Dexmedetomidine as Neuroprotective Agent: An Updated Review

open access: yesBrain Sciences, 2021
Dexmedetomidine, selective α2-adrenergic agonist dexmedetomidine, has been widely used clinically for sedation and anesthesia. The role of dexmedetomidine has been an interesting topic of neonatological and anesthetic research since a series of ...
Zaara Liaquat   +4 more
doaj   +1 more source

Altered of apoptotic markers of both extrinsic and intrinsic pathways induced by hepatitis C virus infection in peripheral blood mononuclear cells

open access: yesVirology Journal, 2012
Background Chronic hepatitis C (CHC) has emerged as a leading cause of cirrhosis in the U.S. and across the world. To understand the role of apoptotic pathways in hepatitis C virus (HCV) infection, we studied the mRNA and protein expression patterns of ...
Albertoni Guilherme   +11 more
doaj   +1 more source

Caspase-8 Potentiates Triglyceride (TG)-Induced Cell Death of THP-1 Macrophages via a Positive Feedback Loop

open access: yesKorean Journal of Clinical Laboratory Science, 2021
Hypertriglyceridemia is the main risk factor for atherosclerosis. It is reported that triglyceride (TG) induces macrophage cell death, and is involved in the formation of plaques and development of atherosclerosis.
Byung Chul Jung   +3 more
doaj   +1 more source

Investigation of the cellular response to bone fractures: evidence for flexoelectricity [PDF]

open access: yesScientific Reports volume 10, Article number: 254 (2020), 2020
The recent discovery of bone flexoelectricity (electrical polarization induced by strain gradient) suggests that flexoelectricity could have physiological effects in bones, and specifically near bone fractures, where flexoelectricity is theoretically highest. Here, we report a cytological study of the interaction between crack stress and bone cells. We
arxiv   +1 more source

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