Results 21 to 30 of about 7,657,629 (247)

Caspase-8 RNA half-life and CpG positions on its promoter proximal region.

open access: yes, 2022
(A) Quantification of caspase-8 mRNA to check its half-life post transcriptional block (using Actinomycin-D) (n = 3). (B) In situ hybridization with anti-sense and sense probe of caspase-8 RNA (in vitro) [scale = 10 μm].
Akshay Hegde (13813404)   +7 more
core   +1 more source

Caspase-3 and Caspase-8 in Patients with Nodular Goiter and Autoimmune Thyroiditis

open access: yesGalician Medical Journal, 2016
The article presents results of the comparative analysis of peroxidation process activity of caspase-3 and caspase-8 in patients with thyroid adenoma (TA) and nodular goiter with autoimmune thyroiditis (NGAIT).
M. I. Sheremet   +3 more
doaj   +1 more source

TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis

open access: yesCell Death Discovery, 2023
Sarcopenia has become a leading cause of disability and mortality in the elderly. It has been reported that programmed cell death (PCD) is associated with the development of sarcopenia that is characterized by reduction of muscle fiber size and number ...
Jingying Wu   +9 more
doaj   +1 more source

Caspase-8 but not caspase-7 influences inflammasome activation to act in control of Brucella abortus infection

open access: yesFrontiers in Microbiology, 2022
Programmed cell death (PCD) is an important mechanism of innate immunity against bacterial pathogens. The innate immune PCD pathway involves the molecules caspase-7 and caspase-8, among others.
Raiany A. Santos   +5 more
doaj   +1 more source

Caspase-8 content in SNU-1 cells.

open access: yes, 2021
Increases in intracellular Caspase-8 compared to blank (untreated) SNU-1 cells upon treatment with 50–5000 nm sized aminated, carboxylated and NF particles for 4 h. Data compared with respect to surface functionalization (A) or particle size (B).
Amrita Banerjee (382658)   +2 more
core   +1 more source

Irisin Protects Against Hind Limb Ischemia Reperfusion Injury

open access: yesDrug Design, Development and Therapy, 2021
Ayşegül Küçük,1,* Yücel Polat,2 Aydan Kılıçarslan,3 Nuran Süngü,3 Hakan Kartal,4 Ali Doğan Dursun,5,* Mustafa Arslan6 1Kutahya Health Sciences University, Medical Faculty, Department of Physiology, Kutahya ...
Küçük A   +6 more
doaj  

Expressão gênica de caspases 3 e 8 em timo e baço de ratas recém-desmamadas e imunossuprimidas por glicocorticóide Genic expression of caspases 3 and 8 in thymus and spleen of glicocorticoid-immunossupressed weaned rats

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2005
Determinou-se a expressão gênica das caspases 3 e 8 mediante transcrição reversa de mRNA total e reação em cadeia da polimerase (RT-PCR) para avaliar a apoptose em timo e baço de ratas imunossuprimidas por glicocorticóides.
J.J. Batista   +3 more
doaj   +1 more source

Caspase-9 cleavage: do you need it

open access: yes, 2007
Caspase-9 which is activated by association with the Apaf-1 apoptosome complex cleaves and activates the downstream effector caspases-3 and -7, thereby executing the caspase-cascade and cell death programme.
Davina Twiddy (7582331)   +1 more
core   +6 more sources

Monte Carlo Study Elucidates the Type 1/Type 2 Choice in Apoptotic Death Signaling in Healthy and Cancer Cells

open access: yesCells, 2013
Apoptotic cell death is coordinated through two distinct (type 1 and type 2) intracellular signaling pathways. How the type 1/type 2 choice is made remains a central problem in the biology of apoptosis and has implications for apoptosis related diseases ...
Somkanya C Raychaudhuri   +1 more
doaj   +1 more source

Bcl-xL overexpression decreases GILZ levels and inhibits glucocorticoid-induced activation of caspase-8 and caspase-3 in mouse thymocytes

open access: yesJournal of Translational Autoimmunity, 2020
Glucocorticoids promote thymocyte apoptosis and modulate transcription of numerous regulators of thymic apoptosis. Among these, glucocorticoid-induced leucine zipper (GILZ) is strongly upregulated in the thymus.
Isabella Muscari   +8 more
doaj   +1 more source

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