Results 211 to 220 of about 6,015,666 (337)

Integrated In Silico and In Vivo evaluation of Cassytha filiformis: Molecular insights into caspase-3/8 binding and wound healing effect

Pharmacological Research - Modern Chinese Medicine
Background: Cassytha filiformis is a parasitic vine traditionally used in Chinese traditional medicine (CTM) for its anti-inflammatory, detoxifying, and wound-healing properties.
Soosamma John, Nisha Shri Chengamaraju, Navya A S, Agasa Ramu Mahesh, Bincy Raj   +4 more
doaj  

Caspase-8 in inflammatory diseases: a potential therapeutic target. [PDF]

Cell Mol Biol Lett
Zhang W, Zhu C, Liao Y, Zhou M, Xu W, Zou Z.   +5 more
europepmc   +1 more source

Oxidation of caspase-8 by hypothiocyanous acid enables TNF-mediated necroptosis. [PDF]

J Biol Chem, 2023
Bozonet SM, Magon NJ, Schwartfeger AJ, Konigstorfer A, Heath SG, Vissers MCM, Morris VK, Göbl C, Murphy JM, Salvesen GS, Hampton MB.   +10 more
europepmc   +1 more source

Intestinal Epithelial‐Derived USP13 Alleviates Colonic Inflammation by Suppressing GRP78‐mediated Endoplasmic Reticulum Stress

Advanced Science, EarlyView.
USP13 deficiency in intestinal epithelial cells aggravates DSS‐induced colitis by enhancing ER stress and apoptosis. USP13 interacts with GRP78 and reduces its K63‐linked ubiquitination to alleviate epithelial injury. Restoring USP13 expression or targeting the USP13‐GRP78 axis may represent a promising strategy for treating inflammatory bowel disease ...
Chenchen Qian, Chenghong Hu, Yong Xu, Wentao Xu, Zhe Wang, Wan Gan, Weiyang Tang, Lijiang Huang, Aleksandr V. Samorodov, Yi Wang   +9 more
wiley   +1 more source

Phosphorylated IRF3 promotes GSDME-mediated pyroptosis through RIPK1/FADD/caspase-8 complex formation during mitotic arrest in ovarian cancer. [PDF]

Cell Commun Signal
Gong W, Zhou D, Xu Q, Wang L, Luo M, Zhang Y, Liao Z, Xiong F, Zhao G, Zhao B, Gao Q, Fang Y.   +11 more
europepmc   +1 more source

Caspase-8 activation by cigarette smoke induces pro-inflammatory cell death of human macrophages exposed to lipopolysaccharide. [PDF]

Cell Death Dis, 2023
Cristaldi M, Buscetta M, Cimino M, La Mensa A, Giuffrè MR, Fiore L, Carcione C, Bucchieri F, Rappa F, Coronnello C, Sciaraffa N, Amato S, Aronica TS, Lo Iacono G, Bertani A, Pace E, Cipollina C.   +16 more
europepmc   +1 more source

Bacteroides Fragilis‐Derived Outer Membrane Vesicles Deliver MiR‐5119 and Alleviate Colitis by Targeting PD‐L1 to Inhibit GSDMD‐Mediated Neutrophil Extracellular Trap Formation

Advanced Science, EarlyView.
Bacteroides fragilis‐derived outer membrane vesicles deliver miR‐5119 and alleviate colitis by targeting PD‐L1 to inhibit GSDMD‐mediated neutrophil extracellular trap formation. Abstract Inflammatory bowel disease (IBD) results from a breakdown in the symbiotic relationship between the intestinal commensal microflora and the mucosal immune system.
Yi Yang, Lanmengxi Yang, Yilin Yang, Haiyi Deng, Shiyu Su, Yinxiao Xia, Jin Su, Yuheng Liu, Junwei Wu, Jing Zhang, Yao Liao, Lifu Wang   +11 more
wiley   +1 more source

Polysome Profiling Proves Impaired IL-10 and Caspase-8 Translation in PBMCs of Hemodialysis Patients. [PDF]

Biomolecules
Dawood A, Fiedler R, Markau S, Girndt M, Ulrich C.   +4 more
europepmc   +1 more source

Expression of DR4, DR5, FAS, Caspase-8 and, DDIAS Genes in AML Patients. [PDF]

Med J Islam Repub Iran, 2023
Naghinezhad J, Alenabi A, Ayatollahi H, Sheikhi M, Sadeghian MH, Khoshnegah Z, Boroumand-Noughabi S.   +6 more
europepmc   +1 more source

Caspase‐8 Collaborates with Caspase‐11 to Drive Tissue Damage and Execution of Endotoxic Shock

Immunity, 2018
P. Mandal, Yanjun Feng, John D Lyons, S. Berger, S. Otani, Alexandra A DeLaney, G. Tharp, Kristal M. Maner-Smith, E. Burd, Michelle C. Schaeffer, Sandra Hoffman, Carol A. Capriotti, L. Roback, Cedrick Young, Zhe Liang, E. Ortlund, Nelson DiPaolo, Steven Bosinger, J. Bertin, P. Gough, I. Brodsky, C. Coopersmith, D. Shayakhmetov, E. Mocarski   +23 more
semanticscholar   +1 more source