Results 81 to 90 of about 328,165 (224)
Advanced Healthcare Materials, EarlyView.This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar +4 more
wiley +1 more source
Cellular Physiology and Biochemistry, 2017 Background: Long noncoding RNA (lncRNA) H19 is emerging as a vital regulatory molecule in the progression of different types of cancer and miR-675 is reported to be embedded in H19's first exon.
Jin Yan +11 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.A flexible electrode loaded with a carbon nanowire network (CC@C‐NWN) is developed for electrochemically generating reactive chlorine species (RCS) from abundant chloride ions in body fluids for tumor therapy. CC@C‐NWN enhances chlorine evolution, inducing redox dysregulation and synergistic apoptosis‐ferroptosis in tumor cells.
Cuinan Jiang +10 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng +6 more
wiley +1 more source
Nonlinear regulation of commitment to apoptosis by simultaneous inhibition of Bcl-2 and XIAP in leukemia and lymphoma cells [PDF]
Apoptosis 16:619-26 (2011), 2011 Apoptosis is a complex pathway regulated by the concerted action of multiple pro- and anti-apoptotic molecules. The intrinsic (mitochondrial) pathway of apoptosis is governed up-stream of mitochondria, by the family of Bcl-2 proteins, and down-stream of mitochondria, by low-probability events, such as apoptosome formation, and by feedback circuits ...
arxiv
BMC Cancer, 2019 Background In epithelial cells, tyrosine kinases induce tyrosine phosphorylation and ubiquitination of the E-cadherin complex, which is responsible for the epithelial-mesenchymal transition (EMT). However, the precise mechanisms remain unclear.
Yunfeng Zhang +5 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Engineered exosome‐based heavy atom‐free nanosensitizers are developed for safe and targeted sono‐photodynamic therapy of solid tumors. The IR820‐TPE‐loaded, biotin‐conjugated exosomes (IR820‐TPE@B‐Exo) demonstrate significant promise for NIR fluorescence imaging‐guided sono‐photodynamic cancer therapy.
Van‐Nghia Nguyen +16 more
wiley +1 more source
Designing for Degradation: Transient Devices Enabled by (Nano)Cellulose
Advanced Materials, EarlyView.Recent progress in transient devices enabled by (nano)cellulosic materials is reviewed. Transiency mechanisms, advantages of nanocelluloses, and a suite of applications are discussed. A circular thinking approach coupled with life cycle assessment is applied to critically revisit the potential, advantages, and challenges of nanocellulose‐enabled ...
Lucas J. Andrew +2 more
wiley +1 more source
Octonion and Split Octonion Representation of SO(8) Symmetry [PDF]
arXiv, 2012 The 8 $\times$ 8 matrix representation of SO(8) Symmetry has been defined by using the direct product of Pauli matrices and Gamma matrices. These 8 $\times$ 8 matrices are being used to describe the rotations in SO(8) symmetry. The comparison of 8$\times$8 matrices with octonions has also been shown.
arxiv
Cleavage of the death domain kinase RIP by Caspase-8 prompts TNF-induced apoptosis [PDF]
, 1999 Ying Lin +3 more
openalex +1 more source