Results 91 to 100 of about 444,442 (201)

Beta-mangostin from activates the intrinsic apoptosis pathway through reactive oxygen species with downregulation of the HSP70 gene in the HL60 cells associated with a G/G cell-cycle arrest

Tumor Biology, 2017
Xanthones are phytochemical compounds found in a number of fruits and vegetables. Characteristically, they are noted to be made of diverse properties based on their biological, biochemical, and pharmacological actions.
Fatima Abdelmutaal Ahmed Omer, Najihah Binti Mohd Hashim, Mohamed Yousif Ibrahim, Firouzeh Dehghan, Maizatulakmal Yahayu, Hamed Karimian, Landa Zeenelabdin Ali Salim, Syam Mohan   +7 more
doaj   +1 more source

Dysregulated Apoptosis Through the Intrinsic Pathway in the Internal Spermatic Vein of Patients With Varicocele

Journal of the Formosan Medical Association, 2009
Apoptosis plays a critical role in various physiological processes. Varicocele is the most common cause of male infertility in adults. The dilated and thickened wall of the internal spermatic vein (ISV) in varicocele is considered similar to that in ...
Jane-Dar Lee, Lieng-Yi Lu, Wen-Hsuan Cheng, Shaw-Yeu Jeng   +3 more
doaj   +1 more source

The heat shock protein 90 inhibitor 17‐AAG induces cell cycle arrest and apoptosis in mantle cell lymphoma cell lines by depleting cyclin D1, Akt, Bid and activating caspase 9 [PDF]

, 2006
Georgios Georgakis, Yang Li, Anas Younes
openalex   +1 more source

The Anti-inflammatory and Anti-apoptotic Role of Crocin against Expression of MMp-9, TIMP-1, MCP-1, Caspase-3, PPARα in Heart Tissue, and Metamorphoses of MicroRNA 188 in Hyperhomocysteinemic Rats [PDF]

, 2019
Samy Hussein, Tahia Ahmed, Aziza Amin, Aliaa H. Ali   +3 more
openalex   +1 more source

Supplementary Figure and Table Legends from Alternative Splicing of Caspase 9 Is Modulated by the Phosphoinositide 3-Kinase/Akt Pathway via Phosphorylation of SRp30a

, 2023
Jacqueline C. Shultz, Rachel W. Goehe, Dayanjan S. Wijesinghe, Charuta Murudkar, Amy J. Hawkins, Jerry W. Shay, John D. Minna, Charles E. Chalfant   +7 more
openalex   +1 more source

Apoptosis pathways induced by recombinant adenovirus in cancer cells [PDF]

, 2010
Apoptosis, or programmed cell death, is an essential physiological process that plays a critical role in development and tissue homeostasis. Expression of VP2 gene derived from infectious bursal disease virus (IBDV) has been shown to be able to induce ...
Allaudin, Zeenathul Nazariah, Koh, Choo Yan   +1 more
core  

Specific targeting of human caspases using designed ankyrin repeat proteins [PDF]

, 2017
Caspases play important roles in cell death, differentiation, and proliferation. Due to their high homology, especially of the active site, specific targeting of a particular caspase using substrate analogues is very difficult.
Ackermann, Rafael, Barandun, Jonas, Bühlmann, Martin, Flütsch, Andreas, Grütter, Markus G., Schroeder, Thilo   +5 more
core  

Paeoniflorin improves cardiac function and decreases adverse postinfarction left ventricular remodeling in a rat model of acute myocardial infarction

Drug Design, Development and Therapy, 2018
Hengwen Chen,* Yan Dong,* Xuanhui He, Jun Li, Jie Wang Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China *These authors contributed equally to this work Background: Paeoniflorin (PF) is the active component of ...
Chen H, Dong Y, He X, Li J, Wang J
doaj  

Nitric oxide and thioredoxin modulate the activity of caspase 9 in HepG2 cells. [PDF]

Biochim Biophys Acta Gen Subj, 2023
Chakraborty S, Choudhuri A, Mishra A, Bhattacharyya C, Billiar TR, Stoyanovsky DA, Sengupta R.   +6 more
europepmc   +1 more source

Antimycin A–induced killing of HL‐60 cells: Apoptosis initiated from within mitochondria does not necessarily proceed via caspase 9 [PDF]

, 2005
Malcolm A. King
openalex   +1 more source