Results 21 to 30 of about 4,742,958 (308)
Caspase‐9 acts as a regulator of necroptotic cell death
The FEBS Journal, 2021 Necroptosis is a regulated necrotic‐like cell death modality which has come into the focus of attention since it is known to contribute to the pathogenesis of many inflammatory and degenerative diseases as well as to tumor regulation.
T. Molnár +16 more
semanticscholar +1 more source
Diagnostics, 2021 Ovarian cancer remains a major diagnostic and therapeutic problem in modern gynecological oncology. For this reason, research which focuses on the search for new diagnostic markers and the assessment of their possible usefulness in clinical practice is ...
Aleksandra Mielczarek-Palacz +2 more
doaj +1 more source
GENETIC POLYMORHISM OF CASPASE 8 AND 9 IN IRAQ
The Iraqi Journal of Agricultural science, 2022 This study examined the potential association between polymorphisms of Caspase 9 −293del (rs4645982) and Caspase8−652 6N ins / del (rs3834129) and the danger of acute and chronic myeloid leukaemia in Iraqi population.
Duaa Abdullah , Reema M. Aloubaidy
doaj +1 more source
Astaxanthin effect on apoptotic biomarkers in methotrexate-induced liver injury
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2022 Methotrexate is used in the treatment of cancer, psoriasis, rheumatoid arthritis and several other disorders. It has a hepatotoxic potential side effect. Patients who have no access to alternative medications face a serious challenge as a result.
Sarah Saad Hamdan +2 more
doaj +1 more source
International Journal of Biochemistry and Cell Biology, 2020 Caspase-9 is a member of caspase family of cysteine proteases that have been implicated in apoptosis and cytokine processing. When cells receive apoptotic stimuli, mitochondria releases cytochrome c which then binds to Apaf-1, the mammalian Ced-4 ...
K. Kuida
semanticscholar +1 more source
Caspase-9 suppresses metastatic behavior of MDA-MB-231 cells in an adaptive organoid model. [PDF]
Sci RepCaspase-9, a cysteine-aspartate protease traditionally associated with intrinsic apoptosis, has recently emerged as having non-apoptotic roles, including influencing cell migration—an aspect that has received limited attention in existing studies. In our
Falahi F +3 more
europepmc +2 more sources
Binding and Kinetic Analysis of Human Protein Phosphatase PP2A Interactions with Caspase 9 Protein and the Interfering Peptide C9h. [PDF]
Pharmaceutics, 2022 The serine/threonine phosphatase PP2A and the cysteine protease Caspase 9 are two proteins involved in physiological and pathological processes, including cancer and apoptosis.
Dorgham K +5 more
europepmc +2 more sources
Diagnostics, 2021 (1) Background: The estimation of the post mortem interval (PMI) is a challenge for forensic pathologists because data emerging from methods commonly applied are not always conclusive, since several conditions exist that may affect the reliability of ...
Cristina Mondello +10 more
doaj +1 more source
What if planet 9 has satellites? [PDF]
ApJ 944, 172 (2023), 2023 In the past decade, numerical simulations started to reveal the possible existence of planet 9 in our solar system. The planet 9 scenario can provide an excellent explanation to the clustering in orbital elements for Kuiper Belt objects. However, no optical counterpart has been observed so far to verify the planet 9 scenario.
arxiv +1 more source
BMC Complementary Medicine and Therapies, 2020 Background The Chinese herbal compound Heshouwuyin has been shown to downregulate the apoptotic rate of testicular tissue cells in Wistar naturally aging rats, and this effect might be related to the mitochondrial pathway [15].
Hongjie Wang +8 more
semanticscholar +1 more source