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Caspases and apoptosis

Essays in Biochemistry, 2002
The ability of metazoan cells to undergo programmed cell death is vital to both the precise development and long-term survival of the mature adult. Cell deaths that result from engagement of this programme end in apoptosis, the ordered dismantling of the cell that results in its 'silent' demise, in which packaged cell fragments are removed by ...
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Death without caspases, caspases without death

Trends in Cell Biology, 2004
Apoptosis is a conserved cell-death process displaying characteristic morphological and molecular changes including activation of caspase proteases. Recent work challenges the accepted roles of these proteases. New investigations in mice and the nematode Caenorhabditis elegans suggest that there could be caspase-independent pathways leading to cell ...
Mary C, Abraham, Shai, Shaham
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Caspase cascades and caspase targets

2000
Apoptosis is an evolutionarily conserved form of cell suicide. Cells that die by apoptosis are disassembled in a stereotypical manner resulting in a characteristic ‘apoptotic morphology’. It was this characteristic, uniform morphology displayed by cells during apoptosis which led to the assumption that cells contain a similar execution machinery ...
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Caspases and Their Substrates

Cold Spring Harbor Perspectives in Biology, 2022
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Caspase Family

2012
Boucher, Dave, Denault, Jean-Bernard
openaire   +3 more sources

Caspase-8 and Caspase-10

2013
Bram J. van Raam, Guy S. Salvesen
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Caspases: their intracellular localization and translocation during apoptosis

Cell Death and Differentiation, 1999
Boris Zhivotovsky   +2 more
exaly  

Caspase-4 and Caspase-5

2013
Junjun Gao, James A. Wells
openaire   +1 more source

Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells

EMBO Journal, 1997
Howard O Fearnhead   +2 more
exaly  

Mechanism of gasdermin D recognition by inflammatory caspases and their inhibition by a gasdermin D-derived peptide inhibitor

Proceedings of the National Academy of Sciences of the United States of America, 2018
Yinghua Chen   +2 more
exaly  

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