Results 151 to 160 of about 90,413 (210)

Evolution of a Pyroptosis-Apoptosis crosstalk drives non-canonical inflammasome signalling

Grant S, Nicholson E, Chen ZHX, Robson C, Sung A, Viswanathan B, Chang Y, Patel P, Kleppen JP, Ozdenya T, Chen KW, Spicer CD, Boucher D.   +12 more
europepmc   +1 more source

An overview of human inflammasomes: Activation and regulation. [PDF]

J Immunol
Jäger E, Ismaeel S, Stehlik C, Dorfleutner A.   +3 more
europepmc   +1 more source

Evolution of the conformational ensemble and allosteric networks of apoptotic caspases in chordates. [PDF]

Biochem J
Joglekar I, Giridhar MNK, Diaz DA, Deo A, Clark AC.   +4 more
europepmc   +1 more source

Recombinant HALT-1 induces mitochondrial-associated apoptotic mechanism in HeLa cells. [PDF]

Sci Rep
Loo LW, Hwang JS.
europepmc   +1 more source

Nitrogen Mustard Disrupts Bioenergetics and Activates Oxidative Stress-Induced Cell Death Pathways in Human Keratinocytes. [PDF]

Chem Res Toxicol
Jan YH, Michniak-Kohn B, Joseph LB, Laskin DL, Laskin JD.   +4 more
europepmc   +1 more source

Cyclodextrin-Based Nanocarriers for 5-Fluorouracil: Cholesteryl Modification Enhances Antitumor Activity Against Colorectal Cancer Cells. [PDF]

Int J Nanomedicine
Skonieczna B, Maliszewski B, Wasiluk N, Car H, Wilczewska AZ, Misiak P, Niemirowicz-Laskowska K.   +6 more
europepmc   +1 more source

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Caspases and caspase inhibitors

Trends in Biochemical Sciences, 1997
Five years ago, little was known about mechanisms of apoptotic execution. Now, one class of cell-death gene, the cysteine and aspartases (caspases) has come under intensive study. This review discusses the two classes of caspases, the reasons why humans may have so many caspase genes, the growing list of caspase substrates, and viral and ...
P, Villa, S H, Kaufmann, W C, Earnshaw
openaire   +2 more sources

Caspases

Current Protocols in Protein Science, 2001
AbstractCaspases are a family of cysteine proteases with a strict specificity for aspartate residues involved in inflammatory process and programmed cell death. This overview unit provides basic information on their structure, enzymatic activity, substrate specificity, activation,inhibition and their implication in pathologies.
Jean-Bernard, Denault, Guy S, Salvesen
openaire   +2 more sources