Results 211 to 220 of about 80,424 (267)

Clausenidin from Clausena excavata Burm. causes Apoptosis of Liver Cancer in Mice. [PDF]

Asian Pac J Cancer Prev
Waziri PM, Auta R, Imam MU, Chindo BA, Ladan Z, Mohammed ZK, Wayah S, Sani JM, Ayuba GI, Ige OT, Tyoapine D, Agbaji A.   +11 more
europepmc   +1 more source

Fortified Chestnut Honey Triggers Apoptosis in Colon Cancer Cells. [PDF]

Plant Foods Hum Nutr
Iriondo-DeHond A, Morales P, Sánchez-Martín V, Hospital XF, Fernández M, Hierro E, Haza AI.   +6 more
europepmc   +1 more source

Narciclasine triggers apoptosis in osteosarcoma cells via JNK-mediated extrinsic and intrinsic pathways. [PDF]

Int J Med Sci
Yang JS, Chou CH, Chen PN, Hsieh YH, Tang CH, Yang SF, Lu KH.   +6 more
europepmc   +1 more source

Cytochrome c as a central regulator of mitochondrial function in cancer metabolism. [PDF]

Discov Oncol
Shabir A, Sofi S, Jan N, Haq BU, Qayoom H, Mir MA.   +5 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Caspases and caspase inhibitors

Trends in Biochemical Sciences, 1997
Five years ago, little was known about mechanisms of apoptotic execution. Now, one class of cell-death gene, the cysteine and aspartases (caspases) has come under intensive study. This review discusses the two classes of caspases, the reasons why humans may have so many caspase genes, the growing list of caspase substrates, and viral and ...
P, Villa, S H, Kaufmann, W C, Earnshaw
openaire   +2 more sources

Caspases

Current Protocols in Protein Science, 2001
AbstractCaspases are a family of cysteine proteases with a strict specificity for aspartate residues involved in inflammatory process and programmed cell death. This overview unit provides basic information on their structure, enzymatic activity, substrate specificity, activation,inhibition and their implication in pathologies.
Jean-Bernard, Denault, Guy S, Salvesen
openaire   +2 more sources

Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation

Nature Medicine, 2000
Dysregulation of apoptosis contributes to the pathogenesis of many human diseases. As effectors of the apoptotic machinery, caspases are considered potential therapeutic targets. Using an established in vivo model of Fas-mediated apoptosis, we demonstrate here that elimination of certain caspases was compensated in vivo by the activation of other ...
T S, Zheng, S, Hunot, K, Kuida, T, Momoi, A, Srinivasan, D W, Nicholson, Y, Lazebnik, R A, Flavell   +7 more
openaire   +2 more sources

Caspases — An update

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2008
Caspases belong to a family of highly conserved aspartate-specific cysteine proteases and are members of the interleukin-1beta-converting enzyme family, present in multicellular organisms. The caspase gene family consists of 15 mammalian members that are grouped into two major sub-families, namely inflammatory caspases and apoptotic caspases.
Indrajit, Chowdhury, Binu, Tharakan, Ganapathy K, Bhat   +2 more
openaire   +2 more sources

Caspase activation

Biochemical Society Symposia, 2003
Caspase activation is the 'point of no return' commitment to cell death. Synthesized as inactive zymogens, it is essential that the caspases remain inactive until the death signal is received. It is known for the downstream executioner caspases-3 and -7 that the activation event is proteolytic cleavage, and this had been assumed to apply to the ...
Kelly M, Boatright, Guy S, Salvesen
openaire   +2 more sources