Results 41 to 50 of about 3,617 (131)

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

A Case of Anti-Caspr2 Autoimmune Encephalitis Associated with Adenocarcinoma of the Lung

European Journal of Case Reports in Internal Medicine, 2022
Autoimmune encephalitis (AIE) is an inflammatory brain condition with multiple aetiologies but is mainly associated with paraneoplastic syndromes. Several antibodies described in AIE are being investigated in relation to different cancers, including ...
Fábio Pé D’Arca Barbosa, Francisco Vara-Luiz, Ana Albuquerque, Ana Valada Marques, Vanda Spencer   +4 more
doaj   +1 more source

Sequential and Concurrent C5 and Neonatal Fc Receptor Inhibition in Prolonged Myasthenic Crisis due to Advanced Invasive Thymoma‐Associated Myasthenia Gravis: A Case Report and Literature Review

Clinical and Experimental Neuroimmunology, Volume 17, Issue 4, November 2026.
ABSTRACT Thymoma‐associated myasthenia gravis (TAMG) is frequently refractory, particularly when complicated by myasthenic crisis in advanced invasive disease. Complement C5 inhibitors and neonatal Fc receptor (FcRn) inhibitors have expanded the treatment of acetylcholine receptor (AChR) antibody‐positive generalized myasthenia gravis; however, their ...
Yuta Kizuka, Yuriko Nakamura, Kensuke Okada, Yu Okubo, Kaoru Kaseda, Hirofumi Toyama, Keisuke Asakura, Atsuya Takeda, Jin Nakahara, Kei Ishizuchi   +9 more
wiley   +1 more source

Clinical characteristics and long-term outcome of CASPR2 antibody-associated autoimmune encephalitis in children

Italian Journal of Pediatrics
Background Contactin-associated protein-2(CASPR2) antibody-associated autoimmune encephalitis(AE) is rare in children. This study aimed to report the clinical characteristics and long-term outcome of CASPR2 autoimmunity in children to expand the disease ...
Donglei Liao, Saying Zhu, Lifen Yang, Ciliu Zhang, Fang He, Fei Yin, Jing Peng   +6 more
doaj   +1 more source

Anti-NMDA receptor encephalitis and MOG-associated demyelination – a case report with long-term follow-up and a systematic review

BMC Neurology, 2022
Background Overlap syndromes of anti-NMDA receptor encephalitis and MOG-mediated demyelination have been reported. In this case we provide a long-term longitudinal follow-up of clinical and imaging characteristics as well as of antibody dynamics.
Klaus Berek, Astrid Grams, Christian Uprimny, Manuela Prieschl, Melanie Ramberger, Iris Unterberger, Florian Deisenhammer, Markus Reindl, Harald Hegen   +8 more
doaj   +1 more source

Clinical analysis and literature review of anti-contactin-associated protein 2 antibody- associated encephalitis

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To summarize the clinical characteristics of patients with anti- contactin - associated protein 2 (CASPR2) antibody-associated encephalitis.
QIN Hong-ling, LI Qi-hui, LU Yi, QIU Wei, SHU Ya-qing   +4 more
doaj   +1 more source

Frontotemporal Dementia with Parkinsonism and Epilepsy Associated with VGKC Antibodies: Case Report and Literature Review

Case Reports in Neurology, 2021
Antibodies directed against the voltage-gated potassium channel complex (anti-VGKCs) are implicated in several autoimmune conditions including limbic encephalitis and epilepsy. However, emerging evidence suggests that only specific subtypes of anti-VGKCs
Matthew Saint, Vafa Alakbarzade, Brendan McLean   +2 more
doaj   +1 more source

Possible Paraneoplastic Amyotrophic Lateral Sclerosis Presenting as Respiratory Failure in a Breast Cancer Patient: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
In a breast cancer patient with acute hypercapnic respiratory failure, paraneoplastic ALS was diagnosed despite negative onconeural antibodies. Red flags included diaphragmatic paralysis, ESR of 120 mm/h, and CSF protein of 246 mg/dL. Clinicians should consider this diagnosis even when antibody panels are negative.
Maryam Albaji, Khashayar Ashkboos, Kosar Bagherzadeh   +2 more
wiley   +1 more source

Uncommon Pediatric Immune-Mediated Epilepsy: Disease Course, Diagnosis, and Outcome – A Series of Three Cases

Annals of Indian Academy of Neurology
Immune-mediated epilepsy (IME) constitutes a substantial proportion of drug-refractory epilepsies. Rapid diagnosis and prompt immunosuppression are required along with antiseizure medications (ASMs).
Aakash Mahesan, Aradhana Rohil, Prashant Jauhari, Madhavi Tripathi, Biswaroop Chakrabarty, Atin Kumar, Sheffali Gulati   +6 more
doaj   +1 more source

Pyruvate dehydrogenase autoantibodies in autoantibody‐negative patients with seizures are associated with reduced pyruvate dehydrogenase activity

Epilepsia, Volume 67, Issue 8, Page 4078-4094, August 2026.
Abstract Objective We investigated the presence and potential functional relevance of antimitochondrial autoantibodies in patients suspicious for autoimmune encephalitis (AIE) associated with psychiatric symptoms and/or seizures, who were negative for known antineuronal autoantibodies.
Annika Breuer, Chiara A. Hummel, Tobias Baumgartner, Juliane L. Berns, Afaf Milad Said, Isabel Bünger, Susanne Schoch, Gábor Zsurka, Harald Prüss, Wolfram S. Kunz, Rainer Surges, Albert J. Becker, Julika Pitsch   +12 more
wiley   +1 more source