Results 21 to 30 of about 3,617 (131)

Eyelid Tremor in a Patient with Anti-Caspr2 Antibody-Related Encephalitis

Case Reports in Neurology, 2014
We describe the first case of a patient with eyelid tremor probably associated with anti-contactin-associated protein-like 2 (Caspr2) antibody. Encephalitis associated with anti-voltage-gated potassium channel antibody is now attributed to autoantibodies
Shuichi Ueno, Makito Hirano, Hikaru Sakamoto, Susumu Kusunoki, Yusaku Nakamura   +4 more
doaj   +1 more source

Case Report: Prominent Brainstem Involvement in Two Patients With Anti-CASPR2 Antibody-Associated Autoimmune Encephalitis

Frontiers in Immunology, 2021
Anti-contactin-associated protein-like 2 (CASPR2) antibody-associated autoimmune encephalitis is commonly characterized by limbic encephalitis with clinical symptoms of mental and behavior disorders, cognitive impairment, deterioration of memory, and ...
Pei Liu, Pei Liu, Miao Bai, Chao Ma, Yaping Yan, Gejuan Zhang, Songdi Wu, Zunbo Li, Daidi Zhao, Kaixi Ren, Hongzeng Li, Jun Guo   +11 more
doaj   +1 more source

Clinical spectrum and diagnostic value of antibodies against the potassium channel-related protein complex

Neurología (English Edition), 2015
Introduction: Antibodies against a protein complex that includes voltage-gated potassium channels (VGKC) have been reported in patients with limbic encephalitis, peripheral nerve hyperexcitability, Morvan's syndrome, and a large variety of neurological ...
M.T. Montojo, M. Petit-Pedrol, F. Graus, J. Dalmau   +3 more
doaj   +1 more source

A Systematic Review and Meta-Analysis of the Recurrence of Autoimmune Encephalitis. [PDF]

Ann Clin Transl Neurol
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Bai S, Zhang S, Zhang H, Zhang Y, Guo J, Yang X.   +5 more
europepmc   +2 more sources

Phenotypic Spectrum of CASPR2 and LGI1 Antibodies Associated Neurological Disorders in Children

Frontiers in Pediatrics, 2022
ObjectivesThe clinical data of patients with double-positive for leucine-rich glioma-inactivated protein 1 (LGI1) and contactin-associated protein-like 2 (CASPR2) antibodies is limited, particularly for children.
Yan Jiang, Chengbing Tan, Tingsong Li, Xiaojie Song, Jiannan Ma, Zhengxiong Yao, Siqi Hong, Xiujuan Li, Li Jiang, Yuanyuan Luo   +9 more
doaj   +1 more source

Clinical profile and treatment response in patients with CASPR2 antibody-associated neurological disease

Annals of Indian Academy of Neurology, 2021
Background: The clinical spectrum of contactin-associated protein-like 2 (CASPR2) antibody-associated disease is wide and includes Morvan syndrome. Studies describing treatment and long-term outcome are limited.
Sumanth Shivaram, Madhu Nagappa, Doniparthi V Seshagiri, Anita Mahadevan, Yashwanth Gangadhar, T N Sathyaprabha, Vijay Kumavat, Rose D Bharath, Sanjib Sinha, Arun B Taly   +9 more
doaj   +1 more source

Specific overexpression of contactin-associated protein-like 2 and its effects on pain-related behaviour in mice

PAIN Reports
. Introduction:. Hyperexcitability, particularly of DRG neurons, is a key driver of persistent pain states including neuropathic pain. Contactin-associated protein-like 2 (CASPR2) is transmembrane protein known to interact and regulate the function of ...
Mandy Tseng, Steven J. Middleton, Adham Farah, Sarosh R. Irani, John M. Dawes, David L. Bennett   +5 more
doaj   +1 more source

Prevalence of the anti-CASPR2 autoantibody in patients with somatic symptom disorder accompanied by medically unexplained pain

Brain, Behavior, & Immunity - Health
Background: Medically unexplained symptoms (MUS) with pain are classified as somatic symptom disorder (SSD) with pain in the field of psychiatry, although an undetected biological basis may underlie at least some of these cases.
Shingo Katayama, Gayatri Nayanar, Takayuki Suga, Motoko Watanabe, Chihiro Takao, Yojiro Umezaki, Hidehiko Takahashi, Akira Toyofuku, Hiroki Shiwaku   +8 more
doaj   +1 more source

Anti‐LGI1, anti‐GABABR, and Anti‐CASPR2 encephalitides in Asia: A systematic review

Brain and Behavior, 2020
Aim We aim to review the literature to collate and describe features of encephalitides arising from autoantibodies against leucine‐rich glioma‐inactivated 1 (LGI1), gamma aminobutyric acid receptor (GABABR), and contactin‐associated protein‐like 2 ...
Prinska Ghimire, Ujjwal Prakash Khanal, Bikram Prasad Gajurel, Ragesh Karn, Reema Rajbhandari, Sunanda Paudel, Niraj Gautam, Rajeev Ojha   +7 more
doaj   +1 more source

The significance of anti-neuronal antibodies for acute psychiatric disorders: a retrospective case–controlled study

BMC Neuroscience, 2018
Background The clinical significance of anti-neuronal antibodies in patients with psychiatric disorders, but without encephalitis, remains unknown.
Morten B. Schou, Sverre Georg Sæther, Ole Kristian Drange, Karoline Krane-Gartiser, Solveig K. Reitan, Arne E. Vaaler, Daniel Kondziella   +6 more
doaj   +1 more source