Results 11 to 20 of about 219,205 (349)

Lutetium-177–PSMA-617 for Metastatic Castration-Resistant Prostate Cancer

New England Journal of Medicine, 2021
BACKGROUND Metastatic castration-resistant prostate cancer remains fatal despite recent advances. Prostate-specific membrane antigen (PSMA) is highly expressed in metastatic castration-resistant prostate cancer.
A Oliver Sartor, Johann Sebastian de Bono, Kim Chi   +2 more
exaly   +2 more sources

Effect of knife castration on leukocyte cytokine expression and indicators of stress, pain, and inflammation in Korean cattle bull calves [PDF]

Animal Bioscience, 2023
Objective This study investigated the effects of surgical castration on behavior, physiological and inflammatory indicators, and leukocyte cytokine mRNA levels in Korean cattle bull calves. Methods Nineteen Korean cattle bull calves (average body weight,
Seonpil Yoo, Seok-Hyun Beak, Hyeok Joong Kang, Da Jin Sol Jung, Dilla Mareistia Fassah, InHyuk Jeong, Seung Ju Park, Md Najmul Haque, Myunghoo Kim, Myunggi Baik   +9 more
doaj   +1 more source

Abiraterone plus Prednisone in Metastatic, Castration-Sensitive Prostate Cancer

New England Journal of Medicine, 2017
Nobuaki Matsubara, Mustafa ÖzgÜroglu, Andrew Protheroe   +2 more
exaly   +2 more sources

Denosumab versus zoledronic acid for treatment of bone metastases in men with castration-resistant prostate cancer: a randomised, double-blind study

Lancet, The, 2011
Matthew D Smith, Janet E Brown, Lawrence I Karsh   +2 more
exaly   +2 more sources

Effect of short-term fattening period and castration method on productivity, serum testosterone, and economic efficacy in Hanwoo cattle

Journal of Animal Science and Technology, 2023
The purpose of this study was to evaluate the effects of castration method and short-term fattening periods on Hanwoo cattle. Thirty-two Hanwoo calves (average body weight: 148.4 ± 19.8 kg) were used.
Jun Sang Ahn, Eung Gi Kwon, Hyun Jeong Lee, Ui Hyung Kim, Jeong Il Won, Sun Sik Jang, Byung Ki Park   +6 more
doaj   +1 more source

Current therapy and drug resistance in metastatic castration-resistant prostate cancer.

Drug resistance updates, 2023
Castration-resistant prostate cancer (CRPC), especially metastatic castration-resistant prostate cancer (mCRPC) is one of the most prevalent malignancies and main cause of cancer-related death among men in the world. In addition, it is very difficult for
Maoping Cai, Xian-lu Song, Xinan Li, Ming-Kun Chen, Jiading Guo, Dong Yang, Zhanghui Chen, Shan-Chao Zhao   +7 more
semanticscholar   +1 more source

An investigation of the use of ethyl chloride and meloxicam to decrease the pain associated with a single or double incision method of castration in piglets

Frontiers in Pain Research, 2023
Castration is a stressful and painful procedure that can impact swine welfare negatively. The objectives of this study were to (1) evaluate the effect of one incision compared to two incisions and the use of a topical vapocoolant (VAPO; ethyl chloride; a
Arlene Garcia, Mhairi Sutherland, Gizell Vasquez, Adrian Quintana, Garrett Thompson, Jemma Willis, Shelbie Chandler, Kiran Niure, John McGlone   +8 more
doaj   +1 more source

Efficacy of inguinal buffered lidocaine and intranasal flunixin meglumine on mitigating physiological and behavioral responses to pain in castrated piglets

Frontiers in Pain Research, 2023
Managing castration pain on US sow farms is hindered by the lack of Food and Drug Administration (FDA) approved products for mitigating pain. Previous work assessing flunixin meglumine (FM) efficacy in mitigating castration pain has shown the drug to be ...
Magdiel Lopez-Soriano, Victoria Rocha Merenda, Stephanie Anderson, Pedro Henrique Esteves Trindade, Martin S. Leidig, Kristen Messenger, Juliana Bonin Ferreira, Monique Danielle Pairis-Garcia   +7 more
doaj   +1 more source

Apalutamide in Patients With Metastatic Castration-Sensitive Prostate Cancer: Final Survival Analysis of the Randomized, Double-Blind, Phase III TITAN Study

Journal of Clinical Oncology, 2021
PURPOSE The first interim analysis of the phase III, randomized, placebo-controlled TITAN study showed that apalutamide significantly improved overall survival (OS) and radiographic progression-free survival in patients with metastatic castration ...
K. Chi, S. Chowdhury, A. Bjartell, B. Chung, A. J. Pereira de Santana Gomes, R. Given, Á. Juárez Soto, A. Merseburger, M. Özgüroğlu, H. Uemura, D. Ye, S. Brookman-May, S. Mundle, S. McCarthy, J. Larsen, Weili Sun, K. Bevans, Ke Zhang, N. Bandyopadhyay, N. Agarwal   +19 more
semanticscholar   +1 more source

Evaluation of the subcapsular technique for primary closure castration in donkeys (Equus asinus)

Scientific Reports, 2021
This study described the subcapsular technique for primary closure castration in donkeys with special regard to its efficiency and welfare impacts. The study was conducted on twelve adult male donkeys, allocated randomly into two groups; subcapsular ...
Ahmed Ibrahim, Usama T. Mahmoud, Magda M. Ali, Sohair M. M. Ragab   +3 more
doaj   +1 more source