Results 21 to 30 of about 219,205 (349)

A nationwide survey on producer and veterinarian perceptions of the painfulness of procedures and disease states in dairy and beef cattle

Frontiers in Pain Research, 2023
Failure to adequately manage pain in cattle causes suffering and is thus a welfare concern for the livestock industry. The objectives of this study were to summarize caregiver perceptions of the painfulness of various procedures and disease conditions in
Lily N. Edwards-Callaway, Kayleigh P. Keller, Katrina Oselinsky, Elizabeth Johnstone, Catie Cramer, Noa Román-Muñiz, Lorann Stallones, Johann F. Coetzee   +7 more
doaj   +1 more source

Olaparib for Metastatic Castration-Resistant Prostate Cancer.

New England Journal of Medicine, 2020
BACKGROUND Multiple loss-of-function alterations in genes that are involved in DNA repair, including homologous recombination repair, are associated with response to poly(adenosine diphosphate-ribose) polymerase (PARP) inhibition in patients with ...
J. D. de Bono, J. Mateo, K. Fizazi, F. Saad, N. Shore, S. Sandhu, K. Chi, O. Sartor, N. Agarwal, D. Olmos, A. Thiery-Vuillemin, P. Twardowski, N. Mehra, C. Goessl, Jinyu Kang, J. Burgents, Wenting Wu, A. Kohlmann, C. Adelman, M. Hussain   +19 more
semanticscholar   +1 more source

Penolakan Peran Dokter Sebagai Eksekutor Sanksi Hukum Kebiri di Indonesia: Perspektif Filsafat Hukum Islam

Al-Izzah, 2021
Behind the pro-contra polemic of imposing castration legal sanctions for criminals of pedophilia in Indonesia, doctors have a dilemma as a profession that is considered to have medical competence and is worthy of being executors.
Abdul Aziz Harahap, Athoillah Islamy
doaj   +1 more source

Management of patients with advanced prostate cancer-metastatic and/or castration-resistant prostate cancer: report of the Advanced Prostate Cancer Consensus Conference (APCCC) 2022.

European Journal of Cancer, 2023
BACKGROUND Innovations in imaging and molecular characterisation together with novel treatment options have improved outcomes in advanced prostate cancer. However, we still lack high-level evidence in many areas relevant to making management decisions in
S. Gillessen, A. Bossi, I. Davis, J. D. de Bono, K. Fizazi, N. James, N. Mottet, N. Shore, E. Small, M. Smith, C. Sweeney, B. Tombal, E. Antonarakis, A. Aparicio, A. Armstrong, G. Attard, T. Beer, H. Beltran, A. Bjartell, P. Blanchard, A. Briganti, R. Bristow, M. Bulbul, O. Caffo, D. Castellano, E. Castro, Heather H. Cheng, K. Chi, S. Chowdhury, C. Clarke, N. Clarke, G. Daugaard, M. De Santis, I. Durán, R. Eeles, E. Efstathiou, J. Efstathiou, O. Ekeke, C. P. Evans, S. Fanti, F. Feng, V. Fonteyne, N. Fossati, M. Frydenberg, Daniel J. George, M. Gleave, G. Gravis, S. Halabi, D. Heinrich, K. Herrmann, C. Higano, M. Hofman, L. Horvath, M. Hussain, B. Jereczek-Fossa, Rob J Jones, R. Kanesvaran, P. Kellokumpu-Lehtinen, R. Khauli, L. Klotz, G. Kramer, R. Leibowitz, C. Logothetis, B. Mahal, F. Maluf, J. Mateo, D. Matheson, N. Mehra, A. Merseburger, A. Morgans, M. Morris, H. Mrabti, D. Mukherji, D. Murphy, V. Murthy, P. Nguyen, W. Oh, P. Ost, J. O’Sullivan, A. Padhani, C. Pezaro, D. Poon, C. Pritchard, D. Rabah, D. Rathkopf, R. Reiter, M. Rubin, C. Ryan, F. Saad, J. P. Sade, O. Sartor, H. Scher, N. Sharifi, I. Skoneczna, H. Soule, D. Spratt, S. Srinivas, C. Sternberg, T. Steuber, Hiroyoshi Suzuki, M. Sydes, M. Taplin, D. Tilki, L. Türkeri, F. Turco, Hiroji Uemura, H. Uemura, Y. Ürün, C. Vale, I. V. van Oort, N. Vapiwala, J. Walz, K. Yamoah, Dingwei Ye, E. Yu, A. Zapatero, T. Zilli, A. Omlin   +117 more
semanticscholar   +1 more source

Identification of the α2 chain of interleukin‐13 receptor as a potential biomarker for predicting castration resistance of prostate cancer using patient‐derived xenograft models

Cancer Reports, 2023
Background Several treatment strategies use upfront chemotherapy or androgen receptor axis‐targeting therapies for metastatic prostate cancer. However, there are no useful biomarkers for selecting appropriate patients who urgently require these ...
Takahiro Nagai, Naoki Terada, Masato Fujii, Yasuhisa Nagata, Kozue Nakahara, Shoichiro Mukai, Kosuke Okasho, Yuki Kamiyama, Shusuke Akamatsu, Takashi Kobayashi, Kei Iida, Masatsugu Denawa, Masatoshi Hagiwara, Takahiro Inoue, Osamu Ogawa, Toshiyuki Kamoto   +15 more
doaj   +1 more source

Delivering an Immunocastration Vaccine via a Novel Subcutaneous Implant

Animals, 2022
Immunocastration relies on the vaccine-mediated stimulation of an immune response to gonadotropin-releasing hormone (GnRH) in order to interrupt spermatogenesis. This approach offers a less painful alternative to traditional castration approaches but the
Andrew K. Curtis, Douglas E. Jones, Michael Kleinhenz, Shawnee Montgomery, Miriam Martin, Mikaela Weeder, Alyssa Leslie, Balaji Narasimhan, Sean Kelly, Drew R. Magstadt, Alfredo Colina, Johann F. Coetzee   +11 more
doaj   +1 more source

Comparison of Flunixin Meglumine, Meloxicam and Ketoprofen on Mild Visceral Post-Operative Pain in Horses

Animals, 2022
The analgesic efficacy of meloxicam and ketoprofen against equine visceral pain is unclear. The aim of this study was to compare the analgesic efficacy of meloxicam (M) and ketoprofen (K) to flunixin meglumine (F) following inguinal castration.
Louise C. Lemonnier, Chantal Thorin, Antoine Meurice, Alice Dubus, Gwenola Touzot-Jourde, Anne Couroucé, Aurélia A. Leroux   +6 more
doaj   +1 more source

Half-castration is a newly effective method for increasing yield and tenderness of male cattle meat [PDF]

Animal Bioscience, 2022
Objective For improving meat quality especially tenderness, male cattle are usually castrated to removes both the testicles. This study was conducted to evaluate the effect castration method (half- and complete-castration) on meat yield and quality ...
Van-Ba Hoa, Dong-Heon Song, Kuk-Hwan Seol, Sun-Moon Kang, Hyun-Wook Kim, Sun-Sik Jang, Soo-Hyun Cho   +6 more
doaj   +1 more source

Nociception-Induced Changes in Electroencephalographic Activity and FOS Protein Expression in Piglets Undergoing Castration under Isoflurane Anaesthesia

Animals, 2022
The objective of this study was to investigate the electroencephalographic reaction pattern and FOS protein expression in male piglets undergoing surgical castration under light isoflurane anaesthesia with or without local anaesthesia. The experiment was
Judith Reiser, Matthias Kreuzer, Julia Werner, Anna M. Saller, Johannes Fischer, Steffanie Senf, Pauline Deffner, Nora Abendschön, Tanja Groll, Andrea Grott, Regina Miller, Shana Bergmann, Michael H. Erhard, Mathias Ritzmann, Susanne Zöls, Gerhard Schneider, Katja Steiger, Christine Baumgartner   +17 more
doaj   +1 more source

Measurement of Fecal Testosterone Metabolites in Mice: Replacement of Invasive Techniques [PDF]

, 2020
Testosterone is the main reproductive hormone in male vertebrates and conventional methods to measure testosterone rely on invasive blood sampling procedures.
Auer, Kerstin E., Hohlbaum, Katharina, Kußmaul, Marius, Möstl, Erich, Palme, Rupert, Rülicke, Thomas   +5 more
core   +1 more source