Results 41 to 50 of about 77,635 (307)
International Brazilian Journal of Urology, 2012 OBJECTIVE: To analyze the impact of low levels of testosterone induced by orchiectomy and the effect of alpha-tocopherol supplementation on oxidative stress in the urethral sphincter.
Mirian Kracochansky +4 more
doaj +1 more source
Current Advances of Nitric Oxide in Cancer and Anticancer Therapeutics
Vaccines, 2021 Nitric oxide (NO) is a short-lived, ubiquitous signaling molecule that affects numerous critical functions in the body. There are markedly conflicting findings in the literature regarding the bimodal effects of NO in carcinogenesis and tumor progression,
Joel Mintz +7 more
doaj +1 more source
, 2019 OBJECTIVE To describe a closed castration technique in standing equids, report associated complications, and identify potential risk factors. STUDY DESIGN Prospective cohort study of 300 standing equids that were castrated with the Henderson ...
Vidondo, Beatriz +3 more
core +1 more source
Advanced Science, EarlyView.Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang +11 more
wiley +1 more source
Renal phenotype of Et-1 transgenic mice is modulated by androgens
European Journal of Medical Research, 2009 Introduction Activation of the endothelin (ET) system promotes inflammation and fibrosis in various tissues including the kidney. Male ET-1 transgenic mice are characterized by chronic kidney inflammation and renal scarring.
Kalk P +6 more
doaj +1 more source
Advanced Science, EarlyView.This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu +18 more
wiley +1 more source
Jurnal Urologi Indonesia, 2014 Objectives: To demonstrate that intratesticular injection of 20% hypertonic sodium chloride can result in permanent castration and to evaluate serum changes in sodium chloride levels.
Marta Hendry +5 more
doaj +1 more source
Animals, 2021 Castration is one of the most frequently performed surgical procedures in livestock. All methods of castration are associated with a significant degree of pain, affecting the patients’ welfare.
Giulia Guerri +8 more
doaj +1 more source
, 2023 Objective: Lutetium-177 prostate-specific membrane antigen-617 is a novel alternative therapeutic option in metastatic castration-resistant prostate cancer, especially useful for patients who do not respond to standard therapy methods.
Maman, Adem, Adem Maman
core +1 more source