Results 61 to 70 of about 77,635 (307)

Chemical Castration as Punishment [PDF]

open access: yes, 2020
This chapter explores whether chemical castration can be justified as a form of criminal punishment. The author argues that castration via the drug medroxyprogesterone acetate (MPA), or some similar drug, does not achieve the punishment aims of ...
Sifferd, Katrina L.
core  

Sheep farmers’ castration practices.

open access: yes, 2022
Sheep farmers’ castration practices.
Demeke Haile Engidashet (12850750)   +1 more
core   +1 more source

Targeting KDM3B Elicits Anti‐tumor Immunity by Alleviating SHP1–mediated STING Suppression in Triple–Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
P3FI–90 treatment targets KDM3B, reshapes the epigenetic landscape, and suppresses SHP1 expression, thereby activating STING–TBK1–IRF3–type I IFN signaling pathway. Consequently, CD8+ T cells are recruited to the tumor site and activated to produce IFN–γ and GZMB, leading to the killing of TNBC cells.
Xiaolong Wang   +8 more
wiley   +1 more source

Development and Field Validation of Lidocaine-Loaded Castration Bands for Bovine Pain Mitigation

open access: yesAnimals, 2020
Castration is among the most common management procedures performed in the dairy and beef cattle industries and is mainly performed by surgery or elastic banding.
James W. Saville   +11 more
doaj   +1 more source

Anaesthesia for castration of piglets: comparison between intranasal and intramuscular application of ketamine, climazolam and azaperone

open access: yes, 2007
The aim of this study was to compare the effect of an anaesthetic combination given either intramuscularly (IM) or intranasally (IN) for castration of piglets.
Schatzmann, U   +4 more
core   +1 more source

Review: castration – animal welfare considerations

open access: yes, 2023
The castration of male cattle is an integral part of routine farm management. The nature and duration of an animal’s response to castration are dependent on a number of factors, including the method employed, the age of animals, the post-castration ...
Gabriela A. Marquette   +2 more
core   +1 more source

Heat Shock Protein 90: From Molecular Chaperone Function to Therapeutic Targeting in Malignancies

open access: yesAdvanced Science, EarlyView.
In this review, an integrated conceptual framework linking HSP90's molecular chaperone functions to its pathological roles in cancer is proposed. HSP90 serves as a central node that integrates oncogenic signaling, buffers proteotoxic stress, maintains cancer stem cell plasticity, and shapes tumor‐immune interactions, all of which converge to drive ...
Beibei Zhang   +4 more
wiley   +1 more source

‘Seeking Justice, Not Charity’. Medical Experiment Victims’ Struggle with Purposefully Inadequate Compensation

open access: yesEastern European Holocaust Studies
Germany’s initial Wiedergutmachung process did little good for survivors of Nazi medical experiments who struggled with uniquely devastating circumstances.
Weinberger Ruth Jolanda
doaj   +1 more source

Androgen and Oestrogen Affect the Expression of Long Non-Coding RNAs During Phallus Development in a Marsupial

open access: yesNon-Coding RNA, 2018
There is increasing evidence that long non-coding RNAs (lncRNAs) are important for normal reproductive development, yet very few lncRNAs have been identified in phalluses so far.
Yu Chen   +7 more
doaj   +1 more source

Comparative Plasma and Interstitial Fluid Pharmacokinetics of Meloxicam, Flunixin, and Ketoprofen in Neonatal Piglets

open access: yesFrontiers in Veterinary Science, 2020
Piglet castration and tail-docking are routinely performed in the United States without analgesia. Pain medications, predominately non-steroidal anti-inflammatory drugs, are used in the EU/Canada to decrease pain associated with processing and improve ...
Emma Nixon   +3 more
doaj   +1 more source

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