Results 61 to 70 of about 55,213 (259)

Fatalities within seven days after equine standing sedation: A prospective, multicentre study

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Information regarding mortality associated with standing procedures in horses is sparse. Objectives To report data from >12,000 standing sedations. Study Design Confidential, observational, prospective, multicentre, cohort study.
Miguel Gozalo‐Marcilla   +6 more
wiley   +1 more source

FAM107A loss facilitates TTK‐OPTN‐mediated mitophagy to drive docetaxel resistance in castration‐resistant prostate cancer

open access: yesInterdisciplinary Medicine, EarlyView.
In the progression of docetaxel resistance, downregulation of FAM107A releases its transcriptional repression of TTK, leading to TTK upregulation. TTK enhances the interaction and phosphorylation of OPTN. This activates mitophagy in tumor cells, facilitates clearance of damaged mitochondria, reduces intracellular reactive oxygen species accumulation ...
Yishan Zhang   +11 more
wiley   +1 more source

Effects of Topical Anaesthetic and Buccal Meloxicam Treatments on Concurrent Castration and Dehorning of Beef Calves

open access: yesAnimals, 2018
The use of pain relief during castration and dehorning of calves on commercial beef operations can be limited by constraints associated with the delivery of analgesic agents.
Dominique Van der Saag   +6 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik   +3 more
wiley   +1 more source

The Sheep Project (3): A Review of Age‐at‐Death Estimation From Mandible Stage Schemes in the Light of a High Resolution Known‐Age Shetland Sheep Dataset

open access: yesInternational Journal of Osteoarchaeology, EarlyView.
ABSTRACT The largest published dataset of sheep (Ovis aries) cheek tooth wear recorded from known‐age skeletonized mandibles is presented, with raw data disseminated as a supplement. The dataset has previously been used to investigate the influence of sex, nutrition, and breeding status on dental maturation (eruption and wear of individual teeth). Here,
Fay Worley   +4 more
wiley   +1 more source

A Modern Metrical Baseline for Sexing Sheep Horn‐Cores

open access: yesInternational Journal of Osteoarchaeology, EarlyView.
ABSTRACT Sex determination is essential for reconstructing past livestock management, yet the limited skeletal sexual dimorphism of sheep hinders the identification of ewes, rams, and wethers in archaeological assemblages. Horn‐cores are the most sexually dimorphic element of the sheep skeleton, and here, we establish a new metrical baseline for ...
Julia Cussans   +3 more
wiley   +1 more source

Asymmetrical Steps: Osteomorphological and Metric Patterns of Cattle Phalanges to Determine Anatomical Position

open access: yesInternational Journal of Osteoarchaeology, EarlyView.
ABSTRACT This study presents a reproducible framework for identifying the anatomical position of cattle phalanges, integrating both morphological and osteometric approaches for application to modern and zooarchaeological assemblages. The dataset comprises 1853 phalanges from 106 individuals with known and unknown phalangeal position representing ...
Audrey Crabbé   +2 more
wiley   +1 more source

Ineffectiveness of immune checkpoint inhibitors in prostate cancer: is it just a question of ‘‐mabs’?

open access: yesThe Journal of Pathology, EarlyView.
Abstract Prostate cancer (PCa) is the second most common type of neoplasm, currently treated with a variety of therapeutic agents. Although advances in treatment over the past decade have improved overall survival, patients with advanced PCa eventually progress from hormone‐sensitive PCa to metastatic castration‐resistant PCa.
Giuseppe Schepisi   +8 more
wiley   +1 more source

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