Results 71 to 80 of about 77,635 (307)
Advanced Science, EarlyView.Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu +20 more
wiley +1 more source
Advanced Science, EarlyView.Our experimental evidence supports a model in which ALO targets the HSPA8‐CMA‐ATP6V1A axis to induce lysosomal hyperacidification and initiate osmotic and lipidomic stress. These changes are associated with LMP and loss of lysosomal integrity in prostate cancer cells.
Bingzheng An +8 more
wiley +1 more source
Dissociative Anaesthesia During Field and Hospital Conditions for Castration of Colts
Acta Veterinaria Scandinavica, 2006 The principal aim of this study was to evaluate dissociative anaesthesia for castration of colts during field conditions. Three dissociative anaesthetic protocols were evaluated during castration of colts in an animal hospital.
Marntell S, Nyman G, Funkquist P
doaj +1 more source
No evidence for detrimental effect of chemical castration on working ability in Swiss military dogs
, 2019 Hormones influence the social behaviour of dogs. Castration of male dogs induces a reduction of testosterone and has been shown to affect social behaviours associated with aggression and reproduction.
Gfrerer, Nastassja +2 more
core +1 more source
[How should hormone therapy for castration-resistant prostate cancer be continued?] [PDF]
, 2012 After an average of 18-36 months under androgen suppression therapy by surgical castration, LHRH, and steroidal or non-steroidal antiandrogens, almost all patients with metastatic prostate cancer show PSA progression as a sign of androgen-independent but
Spahn, M, Krebs, M
core +1 more source
Animal Research and One Health, EarlyView.This research innovatively illustrates baicalin’s multifaceted mechanisms in enhancing piglets’ intestinal health: modulating bile acid metabolism via probiotics, reinforcing tight junction proteins (ZO‐1/claudin), suppressing TLR4/NF‐κB‐mediated inflammation, whereas promoting growth and reducing diarrhea.
Yuhui Gao +6 more
wiley +1 more source
Animals, 2019 There is great need for veterinary care for working equids worldwide. Addressing this need provides an opportunity for veterinary students to gain primary care experience.
Harold C. Schott +11 more
doaj +1 more source
Animal Research and One Health, EarlyView.This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu +8 more
wiley +1 more source
Background: Castration is the most common surgical procedure in domesticated equids; surgical techniques used and perioperative management vary considerably. Objectives: To identify and chart the current evidence on perioperative complications associated
Busschers, Evita +4 more
core +1 more source