Results 111 to 120 of about 190,565 (312)

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

open access: yesAdvanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li   +4 more
wiley   +1 more source

PROTEIN CATABOLISM IN RAT LIVER NUCLEI.

open access: yes, 1969
PROTEIN CATABOLISM IN RAT LIVER ...
THOMAS HARRISON. CLAUS (7974368)
core  

Studies of Folate Catabolism in the Rat [PDF]

open access: yes
The metabolism of a mixture of [2-14C] and [3',5',7,9-3H]-folic acid was studied in adult male and adult female rats. Both sexes were found to metabolise folic acid to various compounds.
Guest, Anne E.
core   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

open access: yesAdvanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen   +8 more
wiley   +1 more source

THE EFFECT OF NUCLEOTIDES ON PROTEIN CATABOLISM.

open access: yes, 1974
THE EFFECT OF NUCLEOTIDES ON PROTEIN ...
WALLACE ROY. PRATT (7955897)
core  

Impact of Dysfunctional Protein Catabolism on Macrophage Cholesterol Handling

open access: yes, 2019
Protein catabolism in macrophages, which is accomplished mainly through autophagy- lysosomal degradation, ubiquitin-proteasome system, and calpains, is disturbed in atheroprone vessels.
Akira Miyazaki, Takuro Miyazaki
core   +1 more source

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

open access: yesAdvanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang   +5 more
wiley   +1 more source

ACBP is an appetite stimulator across phylogenetic barriers

open access: yesCell Stress, 2020
Frank Madeo   +3 more
doaj   +1 more source

Anabolic and catabolic mediators

open access: yesCurrent Opinion in Clinical Nutrition and Metabolic Care, 1998
Negative N balance, and skeletal muscle wasting are associated with many disease states. Depletion of skeletal muscle mass is recognized as critical to overall survival of the patient and can prolong rehabilitation to normal physiological function following recovery.
openaire   +3 more sources

Regulation of Yolk Catabolism in Early Embryogenesis

open access: yes, 2016
Yolk provides an important source of nutrients during the early development of oviparous (non-platental) organisms. In addition to phosphate and lipids, it is com- posed mainly of vitellogenin proteins packed into membrane-bound compartments called yolk ...
Kuhn, Hallie
core  

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