Results 111 to 120 of about 265,603 (330)

CRP Regulates D-Lactate Oxidation in Shewanella oneidensis MR-1

open access: yesFrontiers in Microbiology, 2017
Shewanella oneidensis MR-1 is a heterotrophic facultative anaerobe that respires using various organic and inorganic compounds. This organism has served as a model to study bacterial metabolic and regulatory systems that facilitate their survival in ...
Takuya Kasai   +2 more
doaj   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang   +9 more
wiley   +1 more source

Tryptophan catabolism reflects disease activity in human tuberculosis.

open access: yesJCI Insight, 2020
There is limited understanding of the role of host metabolism in the pathophysiology of human tuberculosis (TB). Using high resolution metabolomics with an unbiased approach to metabolic pathway analysis, we discovered that the tryptophan pathway is ...
J. Collins   +17 more
semanticscholar   +1 more source

In vivo local co-delivery of recombinant human bone morphogenetic protein-7 and pamidronate via poly-D, L-lactic acid [PDF]

open access: yesEuropean Cells & Materials, 2010
The effects of bone anabolic agents such as bone morphogenetic proteins (BMPs) have the potential to be augmented by co-treatment with an anti-catabolic such as a bisphosphonate.
NYC Yu   +6 more
doaj  

Oxidative Catabolism of Tetrahydropterins [PDF]

open access: yes
Mixed labelled folic acid was administerd to rats. Exposure to N2O was used to give an insight into the major route of scission within the monoglutamate pool, results suggest that THF formed during transport from the gut lumen to the plasma is the major ...
Stankiewicz, Margaret J.
core   +1 more source

Regulation of Yolk Catabolism in Early Embryogenesis

open access: yes, 2016
Yolk provides an important source of nutrients during the early development of oviparous (non-platental) organisms. In addition to phosphate and lipids, it is com- posed mainly of vitellogenin proteins packed into membrane-bound compartments called yolk ...
Kuhn, Hallie
core   +3 more sources

Neuroendocrine Balance Index: an Indicator of Metabolic Response to Surgical Stress in Cardiac Surgery

open access: yesУкраїнський журнал серцево-судинної хірургії
Aim. To analyse the dynamics of the Neuroendocrine Balance Index (NEBI = ln(Cortisol/PRL)) during the perioperative period of coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) in order to evaluate its potential as an integrative ...
Lada O. Sobanska, Volodymyr I. Cherniy
doaj   +1 more source

Vascularized Liver‐on‐a‐Microsphere Reveals Alanine‐Glucose Metabolism‐Driven Regulation of Liver Function and Injury

open access: yesAdvanced Science, EarlyView.
A vascularized liver‐on‐a‐microsphere system is developed to recreate lobule‐like cellular organization and endothelial barrier function within compartmentalized hydrogel particles. The platform enhances hepatic performance and reveals alanine‐glucose cycle activation linked to improved detoxification capacity, offering a high‐throughput microscale ...
Jingyang Li   +9 more
wiley   +1 more source

Polyamine Catabolism in Plants: A Universal Process With Diverse Functions

open access: yesFrontiers in Plant Science, 2019
Polyamine (PA) catabolic processes are performed by copper-containing amine oxidases (CuAOs) and flavin-containing PA oxidases (PAOs). So far, several CuAOs and PAOs have been identified in many plant species.
Wei Wang   +4 more
semanticscholar   +1 more source

Exploring Mechanotransduction and Inflammation in Human Cartilaginous Endplate Cells in Blended Collagen–Agarose Hydrogels Under Cyclic Compression

open access: yesGels
Little is known about cartilaginous endplate (CEP) mechanobiology or how it changes in a catabolic microenvironment, partly due to difficulties in conducting mechanotransduction in vitro.
Katherine B. Crump   +6 more
doaj   +1 more source

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