Results 41 to 50 of about 221,645 (319)
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Dark matter voids in the SDSS galaxy survey
What do we know about voids in the dark matter distribution given the Sloan Digital Sky Survey (SDSS) and assuming the $\Lambda\mathrm{CDM}$ model? Recent application of the Bayesian inference algorithm BORG to the SDSS Data Release 7 main galaxy sample ...
Hamaus, Nico +4 more
core +3 more sources
Re-calibration of SDF/SXDS Photometric Catalogs of Suprime-Cam with SDSS Data Release 8 [PDF]
We present photometric recalibration of the Subaru Deep Field (SDF) and Subaru/XMM-Newton Deep Survey (SXDS). Recently, Yamanoi et al. (2012) suggested the existence of a discrepancy between the SDF and SXDS catalogs.
Furusawa, Hisanori +5 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Making Siberian Turkic Printed Collections Visible
In the age of big data, small collections are often overlooked. Too numerically few to cause waves, the issues and problems that affect them are rarely addressed by cataloguing institutions. In the present paper, the author focuses on one such collection
M. J. Erdman
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Libraries and the information services they provide on the Internet face a set of challenges imposed by rapid developments in information technology and remote communications.
Mohamed Helmy
doaj +1 more source
Given their extremely large distances and small apparent sizes, quasars are generally considered as objects with near-zero parallax and proper motion.
Qi-Qi Wu +15 more
doaj +1 more source
Cross-Identification Performance from Simulated Detections: GALEX and SDSS
We investigate the quality of associations of astronomical sources from multi-wavelength observations using simulated detections that are realistic in terms of their astrometric accuracy, small-scale clustering properties and selection functions.
Alexander S. Szalay +11 more
core +1 more source

