Results 121 to 130 of about 390,094 (318)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Estudos metodológicos de nanopartículas catalíticas de Ag-PVP a partir da análise multivariada, aplicadas á catálise de redução de compostos nitroaromáticos [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em QuímicaO presente trabalho relata o preparo, caracterização e estudo da atividade catalítica de nanopartículas de ...
Elias, Welman Curi
core  

DYNAMICS AND CONTROL OF FORCED UNSTEADY-STATE CATALYTIC REACTORS [PDF]

open access: yes, 2004
This research deals with the dynamics and control of forced unsteady-state catalytic reactors and it is focused on two topics: 1. auto-thermal after-treatment of lean VOC mixtures.
Fissore, Davide
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Nanopartículas de prata e prata-paládio estabilizadas pela polietilenoimina linear funcionalizada: formação, caracterização e aplicações catalíticas [PDF]

open access: yes, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em QuímicaA proposta deste trabalho foi a síntese, caracterização e estudo da atividade catalítica de nanopartículas (NPs) de ...
Santos, Kelly de Oliveira
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Catalytic reduction of SO2 by CO over Pt l Au m (CO) n: a first-principles investigation

open access: yes, 2012
The catalytic activities, to the reduction of SO2 by CO, of clusters PtlAum (l + m = 2) with or without preadsorbing CO molecules are investigated using first-principles density functional theory.
Wei, Shi-Hao   +5 more
core   +1 more source

Design and Characterization of Ag@Cu2O-rGO Nanocomposite for the p-Nitrophenol Reduction

open access: yes, 2020
In this paper, we designed Ag nanoparticles coated with a Cu2O shell, which was successfully decorated on reduced graphene oxide (rGO) via a solid-state self-reduction.
Lei Chen, Chao Song, Shuang Guo
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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