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Narcolepsy type 1 is a rare disabling sleep disorder mainly characterized by excessive daytime sleepiness and cataplexy, an emotion-triggered sudden loss of muscle tone.
Elisabeth Ruppert +9 more
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No persistent effect of intravenous immunoglobulins in patients with narcolepsy with cataplexy [PDF]
We report on four patients with narcolepsy with cataplexy (NC), who were treated with high-dose intravenous immunoglobulins (IVIg). Although in some patients transient effects were seen of both objective (multiple sleep latency test and maintenance of ...
Bassetti, C. +3 more
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Sleep-wake disturbances 6 months after traumatic brain injury: a prospective study [PDF]
Sleep-wake disturbances (SWD) are common after traumatic brain injury (TBI). In acute TBI, we recently found decreased CSF levels of hypocretin-1, a wake-promoting neurotransmitter.
Bassetti, Claudio L. +4 more
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Rapid eye movement sleep muscle activity in routine polysomnography as a marker for narcolepsy
Narcolepsy is a chronic neurological disorder characterized by excessive daytime sleepiness and associated symptoms, including cataplexy, sleep paralysis, hypnagogic/hypnopompic hallucinations, and disrupted nocturnal sleep.
Dhirendra Paudel, Yan Xu, Bin Zhang
doaj +1 more source
Issues related to differential diagnosis of epilepsy and narcolepsy
A differential diagnosis of epileptic and non-epileptic paroxysms is particularly difficult to conduct during a neurologist consultation. Narcolepsy is a chronic disease that causes excessive daytime sleepiness.
E. A. Kantimirova, D. V. Dmitrenko
doaj +1 more source
Barnes Hospital Bulletin [PDF]
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1153/thumbnail ...
core +1 more source
CSF prostaglandin D synthase is reduced in excessive daytime sleepiness [PDF]
Lipocalin-type prostaglandin D synthase (L-PGDS) is a brain enzyme, which produces prostaglandin D2, a substance with endogenous somnogenic effects. Using a standardized protocol for immunonephelometric determination of cerebrospinal fluid (CSF) L-PGDS ...
Bassetti, Claudio +2 more
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