Results 81 to 90 of about 5,885 (217)

Transplanting Immortal Orexin Cells in Narcoleptic Mice Rescues Cataplexy

open access: yes, 2022
The sleep disorder narcolepsy is characterized by highly diminished or entirely absent levels of the neuropeptide orexin in the central nervous system. This loss manifests in symptoms such as cataplexy, a sudden and involuntary loss of muscle tone during
Pintwala, Sara Katherine
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Narcolepsy and Cataplexy

open access: yesPediatric Neurology Briefs, 1998
The clinical manifestations and treatment of narcolepsy diagnosed in 51 prepubertal children (29 boys) are reported from the Stanford Sleep Disorder Clinic, Stanford University Medical Center, CA.
J Gordon Millichap
doaj   +1 more source

Cataplexy and its mimics : clinical recognition and management

open access: yes, 2017
This review describes the diagnosis and management of cataplexy: attacks of bilateral loss of muscle tone, triggered by emotions and with preserved consciousness.
Pillen, Sigrid   +19 more
core   +1 more source

Narcolepsy: a review

open access: yesNeuropsychiatric Disease and Treatment, 2011
Gbolagade Sunmaila Akintomide1, Hugh Rickards21Department of Neuropsychiatry, University of Birmingham, 2Department of Neuropsychiatry, The Barberry, Edgbaston, Birmingham, UKAbstract: Narcolepsy is a lifelong sleep disorder characterized by a classic ...
Akintomide GS, Rickards H
doaj  

Investigating the Neural Circuits that Control Cataplexy

open access: yes, 2019
In this thesis I explored a long-standing hypothesis that the paralysis occurring during REM sleep and cataplexy share a common neural mechanism. Cataplexy, a debilitating symptom of narcolepsy, is the abrupt onset of skeletal muscle paralysis during ...
Torontali, Zoltan
core  

Association Study of HLA-DQB1*0602 Allele in Iranian Patients with Narcolepsy

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2017
Narcolepsy is a rare, disabling disorder characterized by excessive daytime sleepiness, cataplexy, hypnagogic hallucinations and sleep paralysis. Several studies demonstrated its association with HLA-DQB1*0602 in various ethnic groups. Our study aimed to
Demeke Geremew   +6 more
doaj  

Melanin-concentrating hormone neurons contribute to dysregulation of rapid eye movement sleep in narcolepsy

open access: yesNeurobiology of Disease, 2018
The lateral hypothalamus contains neurons producing orexins that promote wakefulness and suppress REM sleep as well as neurons producing melanin-concentrating hormone (MCH) that likely promote REM sleep.
Fumito Naganuma   +5 more
doaj   +1 more source

Role of the Catecholamine and Limbic Systems in Narcolepsy/Cataplexy

open access: yes, 2012
In this thesis I investigated the neural circuits that trigger cataplexy in mice. Specifically, I first addressed the theory that cataplexy is a REM sleep disorder.
Burgess, Christian R.
core  

Narcolepsy in early childhood: a case report and a Mini review

open access: yesFrontiers in Pediatrics
Narcolepsy is a sleep-wake disorder with an onset commonly seen in individuals aged 10–30 years. Due to various reasons, the diagnosis of narcolepsy often experiences a delay of at least ten years.
Guorui Liu   +12 more
doaj   +1 more source

Treatment cost of narcolepsy with cataplexy in Central Europe

open access: yes, 2016
Petra Maresova,1 Michal Novotny,2,3 Blanka Klímová,4 Kamil Kuča3,51Department of Economics, Faculty of Informatics and Management, 2Department of Chemistry, Faculty of Science, University of Hradec Králové, 3Biomedical ...
Novotny M   +3 more
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