Results 41 to 50 of about 8,702 (224)
Narcolepsy Following Yellow Fever Vaccination: A Case Report [PDF]
, 2016 Narcolepsy with cataplexy is a rare, but important differential diagnosis for daytime sleepiness and atonic paroxysms in an adolescent. A recent increase in incidence in the pediatric age group probably linked to the use of the Pandemrix influenza ...
Deb K. Pal +3 more
core +3 more sources
Estudo dos linfócitos T CD4, CD8 e B em pacientes com narcolepsia [PDF]
, 2007 Narcolepsy is characterized by excessive daytime sleep and cataplexy. Little is known about the possible difference in pathophysiology between patients with or without cataplexy.
Alves, Gabriela Rodrigues +6 more
core +3 more sources
Anomalous hypothalamic responses to humor in cataplexy.
PLoS ONE, 2008 BackgroundCataplexy is observed in a subset of patients with narcolepsy and affects approximately 1 in 2,000 persons. Cataplexy is most often triggered by strong emotions such as laughter, which can result in transient, yet debilitating, muscle atonia ...
Allan L Reiss +5 more
doaj +1 more source
Feeding-elicited cataplexy in orexin knockout mice [PDF]
, 2009 Mice lacking orexin/hypocretin signaling have sudden episodes of atonia and paralysis during active wakefulness. These events strongly resemble cataplexy, episodes of sudden muscle weakness triggered by strong positive emotions in people with narcolepsy,
Baumann, C R +4 more
core +1 more source
The Impacts of Age and Sex in a Mouse Model of Childhood Narcolepsy
Frontiers in Neuroscience, 2021 Narcolepsy is a sleep disorder caused by selective death of the orexin neurons that often begins in childhood. Orexin neuron loss disinhibits REM sleep during the active period and produces cataplexy, episodes of paralysis during wakefulness.
Alissa A. Coffey +3 more
doaj +1 more source
Increased Numbers of CD4+ T‐Cells in the Hypocretin/Orexin Region of Narcolepsy Type 1
Annals of Neurology, EarlyView.Narcolepsy type 1 (NT1) is presumed to be an autoimmune disorder caused by hypothalamic loss of hypocretin (Hcrt; orexin). In postmortem NT1 brains, we observed an 11‐fold increase of CD4+ T‐cells in the Hcrt region compared with control hypothalami, without a corresponding rise in CD8+ T‐cells.
Ling Shan +5 more
wiley +1 more source
Relato de dois casos de pacientes com narcolepsia com melhora dos sintomas após uso de prednisona [PDF]
, 2007 This article focuses on 2 clinical case reports of narcoleptic patients who experienced an absence of excessive sleepiness during treatment of other illnesses with 40 mg daily intake of prednisone.Este artigo refere-se à discussão de 2 casos de pacientes
Alves, Gabriela Rodrigues +4 more
core +2 more sources
Diurnal fluctuation in the number of hypocretin/orexin and histamine producing: Implication for understanding and treating neuronal loss. [PDF]
, 2017 The loss of specific neuronal phenotypes, as determined by immunohistochemistry, has become a powerful tool for identifying the nature and cause of neurological diseases. Here we show that the number of neurons identified and quantified using this method
McGregor, Ronald +3 more
core +6 more sources
Journal of Neurology, Neurosurgery & Psychiatry, 1977 The case is described of a man who developed attacks of cataplexy, narcolepsy, and sleep paralysis because of microglioma which infiltrated the walls and floor of the IIIrd ventricle and the upper brain stem. The mechanisms by which the pathology is related to the symptoms are discussed.
M, Anderson, M V, Salmon
openaire +2 more sources
Epilepsia Open, EarlyView.Abstract Objective Sialidosis type I (ST‐1) is an autosomal‐recessive, very rare, progressive lysosomal storage disorder caused by pathogenic variants in NEU1. It is clinically characterized by progressive ataxia, myoclonic seizures (MS), bilateral tonic–clonic seizures (BTCS), and distinctive ophthalmological findings.
Janina Gburek‐Augustat +15 more
wiley +1 more source