Results 81 to 90 of about 8,702 (224)
No persistent effect of intravenous immunoglobulins in patients with narcolepsy with cataplexy [PDF]
, 2018 We report on four patients with narcolepsy with cataplexy (NC), who were treated with high-dose intravenous immunoglobulins (IVIg). Although in some patients transient effects were seen of both objective (multiple sleep latency test and maintenance of ...
Bassetti, C. +3 more
core
Orexin system and pathogenesis of sleep-wake cycle disturbances in narcolepsy
Бюллетень сибирской медицины, 2018 Sleep is the one of the most important vital functions of the body. The study of the primary mechanisms that result in disturbance of the sleep-wake cycle is a priority of modern medical science.
Yu. V. Gavrilov +2 more
doaj +1 more source
European Journal of Immunology, Volume 56, Issue 2, February 2026.Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley +1 more source
Brazilian guidelines for the diagnosis of narcolepsy [PDF]
, 2010 Este artigo relata as conclusões da reunião de consenso com médicos especialistas sobre diagnóstico de narcolepsia baseada na revisão dos artigos sobre narcolepsia listados no Medline entre 1980 e 2010.
ALVES, Rosana Cardoso +28 more
core +3 more sources
Persistence of poor sleep predicts the severity of the clinical condition after 6months of standard treatment in patients with eating disorders [PDF]
, 2015 Clinical evidence suggests that eating disorder (ED) patients experience poor sleep even if they rarely complain of it. However, direct empirical evidence supporting this relationship is still sparse.
Battagliese, Gemma +3 more
core +1 more source
Narcolepsy: a case report and review of literature
Neurologijos seminarai, 2019 Narcolepsy is one of the central hypersomnias associated with a tetrad of symptoms: excessive daytime sleepiness, cataplexy, sleep paralysis, and hypnagogic hallucinations.
E. Baltakytė +2 more
doaj +1 more source
Narcolepsy Associated With Streptococcal Infection: A Case Report and Literature Review
Clinical Case Reports, Volume 13, Issue 12, December 2025.ABSTRACT Streptococcal infection–induced narcolepsy is a rare neurological disorder that may be accompanied by severe psychiatric symptoms and social dysfunction. In this case, delayed diagnosis and treatment were followed by progressive symptom worsening, including marked cognitive decline.
Zhenzhen Zhu +5 more
wiley +1 more source
GHB’s Path to Legitimacy: An Administrative and Legislative History of Xyrem [PDF]
, 2012 This paper traces the path of a chemical compound (gamma-hydroxybutyrate, or GHB) from its status as an abused street drug to that of a legitimate, life-altering prescription treatment for a debilitating condition.
Neuman, Ariel
core
Clinical heterogeneity associated with KCNA1 mutations include cataplexy and nonataxic presentations [PDF]
, 2015 Mutations in the KCNA1 gene are known to cause episodic ataxia/myokymia syndrome type 1 (EA1). Here, we describe two families with unique presentations who were enrolled in an IRB-approved study, extensively phenotyped, and whole exome sequencing (WES ...
Agrawal, Pankaj B. +11 more
core +1 more source
Prolonged Detection of GHB Intake in Urine: Are We Finally There?
Drug Testing and Analysis, Volume 17, Issue 12, Page 2429-2446, December 2025.In a randomised placebo‐controlled trial with 30 volunteers, urinary LC‐MS/MS analysis demonstrated that a tentative GHB‐pentose conjugate remained elevated in urine up to 72 h post‐administration. This biomarker showed clear distinction from placebo and may offer extended detection compared to GHB itself, representing a significant step forward in ...
Kathrine B. Faldborg +4 more
wiley +1 more source