Persistence of poor sleep predicts the severity of the clinical condition after 6months of standard treatment in patients with eating disorders [PDF]
Clinical evidence suggests that eating disorder (ED) patients experience poor sleep even if they rarely complain of it. However, direct empirical evidence supporting this relationship is still sparse.
Battagliese, Gemma +3 more
core +1 more source
Actigraphy against 32‐hour polysomnography in patients with suspected idiopathic hypersomnia
Summary Actigraphy, a tool known for investigating sleep–wake patterns at home, lacks scientific validation in hypersomnolent subjects. We aim to validate an actigraphy‐based sleep–wake prediction algorithm against 32‐h continuous polysomnography in patients with suspected idiopathic hypersomnia, and to compare its performance to predict sleep–wake ...
Tugdual Adam +3 more
wiley +1 more source
Selective loss of GABAB receptors in orexin/hypocretin-producing neurons results in disrupted sleep/wakefulness architecture [PDF]
We generated mice with a selective loss of GABAB receptors in orexin neurons. Orexin neurons in these GABAB1<sup>-/-(orexin)</sup> mice showed reduced responsiveness to GABA<sub>A</sub> receptor agonists due to a ...
Bernard Bettler +10 more
core +1 more source
Trypanosoma brucei brucei invasion and T-cell infiltration of the brain parenchyma in experimental sleeping sickness: timing and correlation with functional changes [PDF]
Background: The timing of Trypanosoma brucei entry into the brain parenchyma to initiate the second, meningoencephalitic stage of human African trypanosomiasis or sleeping sickness is currently debated and even parasite invasion of the neuropil has ...
Bentivoglio, Marina +8 more
core +4 more sources
ABSTRACT Parasomnias are abnormal behaviours or mental experiences during sleep or the sleep–wake transition. As disorders of arousal (DOA) or REM sleep behaviour disorder (RBD) can be difficult to capture in the sleep laboratory and may need to be diagnosed in large communities, new home diagnostic devices are being developed, including actigraphy ...
Claudia Picard‐Deland +5 more
wiley +1 more source
Orexin Receptor Antagonism, a New Sleep-Enabling Paradigm: A Proof-of-Concept Clinical Trial [PDF]
Peer ...
Barbanoj, M. J. +22 more
core +2 more sources
Narcolepsy: a case report and review of literature
Narcolepsy is one of the central hypersomnias associated with a tetrad of symptoms: excessive daytime sleepiness, cataplexy, sleep paralysis, and hypnagogic hallucinations.
E. Baltakytė +2 more
doaj +1 more source
Electroencephalogram paroxysmal theta characterizes cataplexy in mice and children [PDF]
Astute control of brain activity states is critical for adaptive behaviours and survival. In mammals and birds, electroencephalographic recordings reveal alternating states of wakefulness, slow wave sleep and paradoxical sleep (or rapid eye movement ...
Dellepiane, Jose M. +7 more
core
Zhongxing Zhang,1 Yves Dauvilliers,2– 4 Giuseppe Plazzi,5,6 Geert Mayer,7 Gert Jan Lammers,8,9 Joan Santamaria,10 Markku Partinen,11 Sebastiaan Overeem,12,13 Rafael del Rio Villegas,14 Karel Sonka,15 Rosa Peraita-Adrados,16 Raphaël Heinzer,17 Aleksandra ...
Zhang Z +25 more
doaj
Parkinsonism with excessive daytime sleepiness: A narcolepsy-like disorder? [PDF]
: Background : Parkinsonian patients with excessive daytime sleepiness (EDS), hallucinations, REM sleep behavior disorder (RBD), short mean sleep latencies, and sleep-onset REM periods (SOREMP) on multiple sleep latency tests (MSLT) have been reported ...
Bassetti, Claudio +4 more
core

