Results 101 to 110 of about 34,133 (279)

Sympathetic Shift and Insular Alteration: Unravelling the Link Between Anxiety and Heart Rate Variability in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Anxiety and autonomic dysfunction are frequent non‐motor symptoms of Parkinson's disease (PD). Their relationship, as well as the neural mechanisms underlying this relationship, remain unexplored. Objectives We aimed to investigate the relationship between cardiovascular functions and anxiety in PD and the structural neural changes ...
Lucia Ricciardi   +9 more
wiley   +1 more source

Purification and Biochemical Characterization of Polyphenol Oxidase Extracted from Wheat Bran (Wan grano)

open access: yesMolecules
Currently, little is known about the characteristics of polyphenol oxidase from wheat bran, which is closely linked to the browning of wheat product. The wheat PPO was purified by ammonium sulfate precipitation, DEAE-Sepharose ion-exchange column, and ...
Kun Yu   +6 more
doaj   +1 more source

Phenoloxidases: catechol oxidase - the temporary employer and laccase - the rising star of vascular plants. [PDF]

open access: yesHortic Res, 2023
Liao J   +11 more
europepmc   +1 more source

Effect on Dyskinesia of the Early Combination of Amantadine to Levodopa‐Therapy in Parkinson's Disease: A Randomized, Placebo‐Controlled Study (PREMANDYSK)

open access: yesMovement Disorders, EarlyView.
Abstract Objective Investigate the efficacy of immediate‐release (IR) amantadine in reducing the risk of peak‐dose dyskinesia in early Parkinson's disease (PD) as add‐on to levodopa. Background While the use of amantadine to manage dyskinesia in PD is well supported by controlled clinical trials, data on its efficacy in patients without motor ...
Olivier Rascol   +106 more
wiley   +1 more source

Induction of Systemic Resistance by Trichoderma Asperellum against Bacterial Wilt of Tomato Caused by Ralstonia Solanacearum [PDF]

open access: yes, 2013
Trichoderma asperellum was used as a biological control agent against bacterial wilt disease caused by Ralstonia solanacearum. The present investigation is focused on the role of defense- related enzymes in imparting resistance to tomato against ...
Fazilath Uzma, .   +2 more
core  

Structure and Mechanism of PhdC, a Prenylated‐Flavin Maturase

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Prenylated flavin mononucleotide (prFMN) is a modified flavin cofactor required by the UbiD family of (de)carboxylase enzymes. While the reduced prFMNH2 form is produced by the flavin prenyltransferase UbiX, the corresponding two‐electron oxidized prFMNiminium form is required to support UbiD catalysis. Thus, oxidative maturation of prFMNH2 is
Dominic R. Whittall   +4 more
wiley   +1 more source

Redox control of multidrug resistance and Its possible modulation by antioxidants [PDF]

open access: yes, 2016
Clinical efficacy of anticancer chemotherapies is dramatically hampered by multidrug resistance (MDR) dependent on inherited traits, acquired defence against toxins, and adaptive mechanisms mounting in tumours.
Cort, A.   +4 more
core   +3 more sources

Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen   +2 more
wiley   +1 more source

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