Results 121 to 130 of about 8,086,442 (367)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Uniqueness of radiomic features in non‐small cell lung cancer

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose The uniqueness of radiomic features, combined with their reproducibility, determines the reliability of radiomic studies. This study is to test the hypothesis that radiomic features extracted from a defined region of interest (ROI) are unique to the underlying structure (e.g., tumor). Approach Two cohorts of non‐small cell lung cancer (
Gary Ge, Jie Zhang
wiley   +1 more source

Internal Kleisli categories [PDF]

open access: yesarXiv, 2009
A construction of Kleisli objects in 2-categories of noncartesian internal categories or categories internal to monoidal categories is presented.
arxiv  

Homotopy Theory in Abelian Categories [PDF]

open access: yesCanadian Journal of Mathematics, 1962
The concept of homotopy for homomorphisms of modules, suggested by analogy with fundamental properties of the topological homotopy, was developed by Eckmann and Hilton (3; 9; 10). In the present paper, this concept of homotopy is generalized to additive categories with an additional structure, and the theory of homotopy, including in particular various
openaire   +3 more sources

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

Joint application of hybrid iterative reconstruction and adaptive filters on neck‐and‐shoulder CT imaging: A clinical evaluation

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose To assess whether the joint application of hybrid iterative reconstruction (HIR) and an adaptive filter (AF) could reduce streak artifacts and improve image quality of neck‐and‐shoulder computed tomography (CT). Methods This study included 96 patients with suspicious neck lesions who underwent a routine nonenhanced scan on a 64‐slice ...
Wenfeng Jin   +6 more
wiley   +1 more source

2 Category of FRBSU Monoidal Categories and Crossed Modules [PDF]

open access: yesarXiv, 2015
In that paper, we prove that the collection of all FRBSU monoidal categories and the collection of all crossed modules form a 2 category.
arxiv  

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

On the validity of the definition of a complement-classifier

open access: yesZagadnienia Filozoficzne w Nauce, 2020
It is well-established that topos theory is inherently connected with intuitionistic logic. In recent times several works appeared concerning so-called complement-toposes (co-toposes), which are allegedly connected to the dual to intuitionistic logic. In
Mariusz Stopa
doaj  

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