Results 51 to 60 of about 2,348,941 (273)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Fundamentals of soft category theory

open access: yesBulletin of Computational Applied Mathematics, 2018
The soft category theory offers a way to study soft theories developed so far more generally. The main purpose of this paper is to introduce the basic algebraic operations in soft categories, and for that we introduce some algebraic operations, like ...
Sujit Kumar Sardar   +2 more
doaj  

Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence

open access: yes
Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari   +9 more
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Architecture, Analysis, and Design of Systems Using Extensions of Category Theory

open access: yesIEEE Open Journal of Systems Engineering
The engineering of systems has lacked the scientific and mathematical underpinnings enjoyed by traditional engineering disciplines. Earlier work of the authors formulated advanced mathematical methods for architecture definition and the use of model ...
Charles E. Dickerson   +1 more
doaj   +1 more source

Obstruction theory in model categories

open access: yesAdvances in Mathematics, 2004
17 pages.
Christensen, J.Daniel   +2 more
openaire   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

String Diagrams for Premonoidal Categories [PDF]

open access: yesLogical Methods in Computer Science
Premonoidal categories are monoidal categories without the interchange law while effectful categories are premonoidal categories with a chosen monoidal subcategory of interchanging morphisms. In the same sense that string diagrams, pioneered by Joyal and
Mario Román, Paweł Sobociński
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Charisma Heuristic as Cognitive Bias: An Informal Category Theoretic Risk Analysis of the Leadership Influence Process

open access: yesAdministrative Sciences
The notion of charisma has been an important, albeit mysterious, aspect of leadership research for decades. Traditionally, its definition has centered on an individual who, by virtue of possessing certain traits, skills, or behaviors, is considered a ...
James K. Hazy
doaj   +1 more source

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