Results 61 to 70 of about 2,374,826 (325)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Geospatial Modeling of Directions for the Development and Implementation of the Land Administration System at the Regional Level

open access: yesCivil and Environmental Engineering
The article is devoted to researching the topical issue of the development and implementation of a modern land administration system as a direction of land relations, considering the development of geo-information systems, mathematical modeling tools and
Bieliatynskyi Andrii   +4 more
doaj   +1 more source

Theory of Interface: Category Theory, Directed Networks and Evolution of Biological Networks [PDF]

open access: yes, 2012
Biological networks have two modes. The first mode is static: a network is a passage on which something flows. The second mode is dynamic: a network is a pattern constructed by gluing functions of entities constituting the network.
Haruna, Taichi
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Quantum Structures and Category Theory

open access: yesAdvances in Electrical and Electronic Engineering, 2004
The methods and constructions of category theory are suitable tools for studying quantum structures and generalized probability. The aim of the present paper is to support our claim via several examples and to motivate further research in this area.
Roman Fric
doaj  

Structural Similarity: Formalizing Analogies Using Category Theory

open access: yesLogics
Analogies are an important part of human cognition for learning and discovering new concepts. There are many different approaches to defining analogies and how new ones can be found or constructed.
Claire Ott
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Fundamentals of soft category theory

open access: yesBulletin of Computational Applied Mathematics, 2018
The soft category theory offers a way to study soft theories developed so far more generally. The main purpose of this paper is to introduce the basic algebraic operations in soft categories, and for that we introduce some algebraic operations, like ...
Sujit Kumar Sardar   +2 more
doaj  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Home - About - Disclaimer - Privacy