Results 61 to 70 of about 6,408,999 (296)

Fundamentals of soft category theory

open access: yesBulletin of Computational Applied Mathematics, 2018
The soft category theory offers a way to study soft theories developed so far more generally. The main purpose of this paper is to introduce the basic algebraic operations in soft categories, and for that we introduce some algebraic operations, like ...
Sujit Kumar Sardar   +2 more
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Architecture, Analysis, and Design of Systems Using Extensions of Category Theory

open access: yesIEEE Open Journal of Systems Engineering
The engineering of systems has lacked the scientific and mathematical underpinnings enjoyed by traditional engineering disciplines. Earlier work of the authors formulated advanced mathematical methods for architecture definition and the use of model ...
Charles E. Dickerson   +1 more
doaj   +1 more source

Categories of theories and interpretations

open access: yes, 2006
In this paper we study categories of theories and interpretations. In these categories, notions of sameness of theories, like synonymy, bi-interpretability and mutual interpretability, take the form of isomorphism. We study the usual notions like monomorphism and product in the various theories.
openaire   +3 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Charisma Heuristic as Cognitive Bias: An Informal Category Theoretic Risk Analysis of the Leadership Influence Process

open access: yesAdministrative Sciences
The notion of charisma has been an important, albeit mysterious, aspect of leadership research for decades. Traditionally, its definition has centered on an individual who, by virtue of possessing certain traits, skills, or behaviors, is considered a ...
James K. Hazy
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Paranatural Category Theory [PDF]

open access: yes, 2023
We establish and advocate for a novel branch of category theory, centered around strong dinatural transformations (herein known as "paranatural transformations"). Paranatural transformations generalize natural transformations to mixed-variant difunctors,
Neumann, Jacob
core   +1 more source

Filozoficznie prowokująca teoria kategorii

open access: yesZagadnienia Filozoficzne w Nauce, 2018
Recenzja książki: Elaine Landry (red.), Categories for the Working Philosopher, Oxford University Press, Oxford, 2017, ss. xiv+471.
Michał Heller
doaj  

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