Results 61 to 70 of about 6,408,999 (296)
Fundamentals of soft category theory
The soft category theory offers a way to study soft theories developed so far more generally. The main purpose of this paper is to introduce the basic algebraic operations in soft categories, and for that we introduce some algebraic operations, like ...
Sujit Kumar Sardar +2 more
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Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Architecture, Analysis, and Design of Systems Using Extensions of Category Theory
The engineering of systems has lacked the scientific and mathematical underpinnings enjoyed by traditional engineering disciplines. Earlier work of the authors formulated advanced mathematical methods for architecture definition and the use of model ...
Charles E. Dickerson +1 more
doaj +1 more source
Categories of theories and interpretations
In this paper we study categories of theories and interpretations. In these categories, notions of sameness of theories, like synonymy, bi-interpretability and mutual interpretability, take the form of isomorphism. We study the usual notions like monomorphism and product in the various theories.
openaire +3 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The notion of charisma has been an important, albeit mysterious, aspect of leadership research for decades. Traditionally, its definition has centered on an individual who, by virtue of possessing certain traits, skills, or behaviors, is considered a ...
James K. Hazy
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Paranatural Category Theory [PDF]
We establish and advocate for a novel branch of category theory, centered around strong dinatural transformations (herein known as "paranatural transformations"). Paranatural transformations generalize natural transformations to mixed-variant difunctors,
Neumann, Jacob
core +1 more source
Filozoficznie prowokująca teoria kategorii
Recenzja książki: Elaine Landry (red.), Categories for the Working Philosopher, Oxford University Press, Oxford, 2017, ss. xiv+471.
Michał Heller
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