Results 81 to 90 of about 2,362,169 (271)
In category theory, the use of string diagrams is well known to aid in the intuitive understanding of certain concepts, particularly when dealing with adjunctions and monoidal categories. We show that string diagrams are also useful in exploring fundamental properties of basic concepts in category theory, such as universal properties, (co)limits, Kan ...
openaire +2 more sources
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Open Markov Processes: A Compositional Perspective on Non-Equilibrium Steady States in Biology
In recent work, Baez, Fong and the author introduced a framework for describing Markov processes equipped with a detailed balanced equilibrium as open systems of a certain type.
Blake S. Pollard
doaj +1 more source
Mackey functors on compact closed categories
We develop and extend the theory of Mackey functors as an application of enriched category theory. We define Mackey functors on a lextensive category $\E$ and investigate the properties of the category of Mackey functors on $\E$.
Panchadcharam, Elango, Street, Ross
core +1 more source
Type theories in category theory
We introduce basic notions in category theory to type theorists, including comprehension categories, categories with attributes, contextual categories, type categories, and categories with families along with additional discussions that are not very closely related to type theories by listing definitions, lemmata (with detailed, diagram-rich proofs ...
openaire +2 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
“Is logic a physical variable?” Introduction to the Special Issue
“Is logic a physical variable?” This thought-provoking question was put forward by Michael Heller during the public lecture “Category Theory and Mathematical Structures of the Universe” delivered on 30th March 2017 at the National Quantum Information ...
Michał Eckstein, Bartłomiej Skowron
doaj
An Order-Theoretic Quantification of Contextuality
In this essay, I develop order-theoretic notions of determinism and contextuality on domains and topoi. In the process, I develop a method for quantifying contextuality and show that the order-theoretic sense of contextuality is analogous to the sense ...
Ian T. Durham
doaj +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source

