Results 81 to 90 of about 6,632,351 (302)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Category Free Category Theory and Its Philosophical Implications [PDF]

open access: yes, 2016
There exists a dispute in philosophy, going back at least to Leibniz, whether is it possible to view the world as a network of relations and relations between relations with the role of objects, between which these relations hold, entirely eliminated ...
Heller, Michael
core  

String Diagrams for Premonoidal Categories [PDF]

open access: yesLogical Methods in Computer Science
Premonoidal categories are monoidal categories without the interchange law while effectful categories are premonoidal categories with a chosen monoidal subcategory of interchanging morphisms. In the same sense that string diagrams, pioneered by Joyal and
Mario Román, Paweł Sobociński
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Category Theory and Universal Property [PDF]

open access: yes, 2019
Category theory unifies and formalizes the mathematical structure and concepts in a way that various areas of interest can be connected. For example, many have learned about the sets and its functions, the vector spaces and its linear transformation, and
Zhang, Niuniu
core  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Level-Agnostic Representations of Interacting Agents

open access: yesMathematics
The study of the interactions among intentional agents, with rationality being the main source of intentional behavior, requires mathematical tools capable of capturing systemic effects. Here, we choose an alternative toolbox based on Category Theory. We
Fernando Tohmé, Andrés Fioriti
doaj   +1 more source

A critical analysis of the philosophical motivations and development of the concept of the field of rationality as a representation of the fundamental ontology of the physical reality

open access: yesZagadnienia Filozoficzne w Nauce, 2022
The unusual applicability of mathematics to the description of the physical reality still remains a major investigative task for philosophers, physicists, mathematicians and cognitive scientists.
Wojciech Grygiel
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

What is Category Theory?

open access: yes, 2006
After giving a short description of the evolution of category theory, the paper sketches a tentative answer to the question constituting the title of the ...
Marquis, Jean-Pierre
core   +1 more source

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