Results 81 to 90 of about 6,408,999 (296)

Entropy, Information and Complexity or Which Aims the Arrow of Time?

open access: yesEntropy, 2015
In this article, we analyze the interrelationships among such notions as entropy, information, complexity, order and chaos and show using the theory of categories how to generalize the second law of thermodynamics as a law of increasing generalized ...
George E. Mikhailovsky   +1 more
doaj   +1 more source

Tilting objects in functor category [PDF]

open access: yes, 2022
Given a ring R, one can consider the category of additive contravariant functors from the category of finitely presented R-modules to the abelian groups, which turns out to be a Grothendieck category.
Cangemi, Domenico
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Semi-Substructural Logics à la Lambek with Symmetry

open access: yesBulletin of the Section of Logic
This work studies the proof theory and ternary relational semantics of left (right) skew monoidal closed categories and skew monoidal bi-closed categories, both symmetric and non-symmetric, from the perspective of non-associative Lambek calculus ...
Cheng-Syuan Wan
doaj   +1 more source

MENS, an Info-Computational Model for (Neuro-)cognitive Systems Capable of Creativity

open access: yesEntropy, 2012
MENS is a bio-inspired model for higher level cognitive systems; it is an application of the Memory Evolutive Systems developed with Vanbremeersch to model complex multi-scale, multi-agent self-organized systems, such as biological or social systems. Its
Andrée C. Ehresmann
doaj   +1 more source

Complex Systems from the Perspective of Category Theory: I. Functioning of the Adjunction Concept [PDF]

open access: yes, 2003
We develop a category theoretical framework for the comprehension of the information structure associated with a complex system, in terms of families of partial or local information carriers.
Zafiris, Elias
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Formalizing Structural Semiotics: A Category-Theoretic Approach to Actantial Systems

open access: yesAxioms
In this article we present a categorical reconstruction of the actantial model introduced by A. J. Greimas in structural semiotics. Using Spivak and Kent’s framework of ontological logs and schema-based categories, the actantial system is formalized as a
Michael Fowler
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Synthetic fibered $(\infty,1)$-category theory

open access: yes, 2023
summary:We study cocartesian fibrations in the setting of the synthetic $(\infty,1)$-category theory developed in simplicial type theory introduced by Riehl and Shulman.
Weinberger, Jonathan, Buchholtz, Ulrik
core   +1 more source

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