Results 91 to 100 of about 6,408,999 (296)
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Achieving robust environmental responsiveness in early stage architectural spatial layout design remains a critical challenge under the imperatives of global carbon neutrality and climate-adaptive building practice.
Rui Liu, Xiaofei Lu
doaj +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
This paper examines the use of algorithms and non-algorithmic models in mathematics and science, especially in biology, during the past century by summarizing the gradual development of a conceptual rationale for non-algorithmic models in biology. First,
Patricia A. Lane
doaj +1 more source
Open Markov Processes: A Compositional Perspective on Non-Equilibrium Steady States in Biology
In recent work, Baez, Fong and the author introduced a framework for describing Markov processes equipped with a detailed balanced equilibrium as open systems of a certain type.
Blake S. Pollard
doaj +1 more source
As categorical dimension increases, classical categorical concepts often become too rigid and must be replaced by appropriately lax analogues. A basic manifestation of this principle is that higher-categorical versions of familiar geometric constructions -- such as cylinders, cones, and suspensions -- are not functorial in the classical sense.
Gepner, D. ; https://orcid.org/0000-0002-7825-9579 +1 more
openaire +3 more sources
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Enriching Laser Powder Bed Fusion Part Data Using Category Theory
Laser powder bed fusion (LPBF) is a promising metal additive manufacturing technology for producing functional components. However, there are still a lot of obstacles to overcome before this technology is considered mature and trustworthy for wider ...
Yuchu Qin +6 more
doaj +1 more source
An Order-Theoretic Quantification of Contextuality
In this essay, I develop order-theoretic notions of determinism and contextuality on domains and topoi. In the process, I develop a method for quantifying contextuality and show that the order-theoretic sense of contextuality is analogous to the sense ...
Ian T. Durham
doaj +1 more source
Challenging the role of implicit processes in probabilistic category learning [PDF]
Considerable interest in the hypothesis that different cognitive tasks recruit qualitatively distinct processing systems has led to the proposal of separate explicit (declarative) and implicit (procedural) systems.
Lagnado, DA, Shanks, DR, Newell, BR
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