Results 61 to 70 of about 2,348,941 (273)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Filozoficznie prowokująca teoria kategorii

open access: yesZagadnienia Filozoficzne w Nauce, 2018
Recenzja książki: Elaine Landry (red.), Categories for the Working Philosopher, Oxford University Press, Oxford, 2017, ss. xiv+471.
Michał Heller
doaj  

A critical analysis of the philosophical motivations and development of the concept of the field of rationality as a representation of the fundamental ontology of the physical reality

open access: yesZagadnienia Filozoficzne w Nauce, 2022
The unusual applicability of mathematics to the description of the physical reality still remains a major investigative task for philosophers, physicists, mathematicians and cognitive scientists.
Wojciech Grygiel
doaj  

Exploring explainable AI: category theory insights into machine learning algorithms

open access: yesMachine Learning: Science and Technology, 2023
Explainable artificial intelligence (XAI) is a growing field that aims to increase the transparency and interpretability of machine learning (ML) models. The aim of this work is to use the categorical properties of learning algorithms in conjunction with
Ares Fabregat-Hernández   +2 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Towards a Convenient Category of Topological Domains [PDF]

open access: yes, 2003
We propose a category of topological spaces that promises to be convenient for the purposes of domain theory as a mathematical theory for modelling computation. Our notion of convenience presupposes the usual properties of domain theory, e.g.
Simpson, Alex
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Entropy, Information and Complexity or Which Aims the Arrow of Time?

open access: yesEntropy, 2015
In this article, we analyze the interrelationships among such notions as entropy, information, complexity, order and chaos and show using the theory of categories how to generalize the second law of thermodynamics as a law of increasing generalized ...
George E. Mikhailovsky   +1 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Category Theory

open access: yes
This book provides a deep foray into category theory, presenting a unique approach to exploring diverse branches of mathematics. From the fundamentals, where the definitions of morphism, object and composition in categories are established, to the application of these concepts in real analysis, linear algebra and general topology, my purpose is to ...
  +5 more sources

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