Results 61 to 70 of about 8,086,442 (367)

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

open access: yesFEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

A First Step to the Categorical Logic of Quantum Programs

open access: yesEntropy, 2020
The long-term goal of our research is to develop a powerful quantum logic which is useful in the formal verification of quantum programs and protocols.
Xin Sun, Feifei He
doaj   +1 more source

Derived categories of NDG categories [PDF]

open access: yesarXiv, 2020
We study $N$-differential graded ($NDG$) categories and their the derived categories. First, we introduce $N$-differential modules over an $NDG$ category $\mathcal{A}$. Then we show that the category $\mathsf{C}_{Ndg}(\mathcal{A})$ of $N$-differential $\mathcal{A}$-modules is a Frobenius category, and that its homotopy category $\mathsf{K}_{Ndg ...
arxiv  

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Introduction: Researching Queer Death

open access: yesWhatever, 2021
The present article serves as an introduction to the dossier What do we talk about when we talk about queer death?, edited by M. Petricola. This introduction briefly interrogates the premises, scope, and objectives of Queer Death Studies (QDS) in such a ...
Mattia Petricola
doaj   +1 more source

Unconventional mRNA processing and degradation pathways for the polycistronic yrzI (spyTA) mRNA in Bacillus subtilis

open access: yesFEBS Letters, EarlyView.
The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet   +4 more
wiley   +1 more source

Fundamentals of soft category theory

open access: yesBulletin of Computational Applied Mathematics, 2018
The soft category theory offers a way to study soft theories developed so far more generally. The main purpose of this paper is to introduce the basic algebraic operations in soft categories, and for that we introduce some algebraic operations, like ...
Sujit Kumar Sardar   +2 more
doaj  

CLASSIFICATION THEORY FOR ACCESSIBLE CATEGORIES [PDF]

open access: yesThe Journal of Symbolic Logic, 2016
AbstractWe show that a number of results on abstract elementary classes (AECs) hold in accessible categories with concrete directed colimits. In particular, we prove a generalization of a recent result of Boney on tameness under a large cardinal assumption.
Jirí Rosický, Michael Lieberman
openaire   +3 more sources

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