Results 71 to 80 of about 8,086,442 (367)

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Quantum Structures and Category Theory

open access: yesAdvances in Electrical and Electronic Engineering, 2004
The methods and constructions of category theory are suitable tools for studying quantum structures and generalized probability. The aim of the present paper is to support our claim via several examples and to motivate further research in this area.
Roman Fric
doaj  

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Abelian categories and definable additive categories [PDF]

open access: yesarXiv, 2012
We consider three (2-)categories and their (anti-)equivalence. They are the category of small abelian categories and exact functors, the category of definable additive categories and interpretation functors, the category of locally coherent abelian categories and coherent morphisms. These categories link algebra, model theory and "geometry".
arxiv  

External triangulation of the homotopy category of exact quasi-category [PDF]

open access: yesarXiv, 2020
Extriangulated categories axiomatize extension-closed subcategories of triangulated categories. We show that the homotopy category of an exact quasi-category can be equipped with a natural extriangulated structure.
arxiv  

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

“Is logic a physical variable?” Introduction to the Special Issue

open access: yesZagadnienia Filozoficzne w Nauce, 2020
“Is logic a physical variable?” This thought-provoking question was put forward by Michael Heller during the public lecture “Category Theory and Mathematical Structures of the Universe” delivered on 30th March 2017 at the National Quantum Information ...
Michał Eckstein, Bartłomiej Skowron
doaj  

Descent and Galois theory for Hopf categories [PDF]

open access: yesarXiv, 2017
Descent theory for linear categories is developed. Given a linear category as an extension of a diagonal category, we introduce descent data, and the category of descent data is isomorphic to the category of representations of the diagonal category, if some flatness assumptions are satisfied.
arxiv  

A pretorsion theory for the category of all categories

open access: yes, 2020
A pretorsion theory for the category of all categories is presented. The associated prekernels and precokernels are calculated for every functor.
openaire   +3 more sources

Who Needs Category Theory?

open access: yesEPiC Series in Computing, 2020
In mathematical applications, category theory remains a contentious issue, with enthusiastic fans and a skepticalmajority. In a muted form this split applies to the authors ofthis note. When we learned that the only mathematically soundfoundation of topological quantum computing in the literature isbased on category theory, the skeptical author ...
Yuri Gurevich, Andreas Blass
openaire   +4 more sources

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