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Cadherins and catenins in development
Current Opinion in Cell Biology, 1996Cadherins and catenins represent key molecules during development. Recent findings demonstrate the involvement of cadherins and catenins in signaling pathways. In a working hypothesis, signaling via beta-catenin regulates the epithelial-mesenchymal transition in vertebrate development.
Otmar Huber
exaly +3 more sources
2004
The adhesion of cells to neighbor cells determines cellular and tissue morphogenesis and regulates major cellular processes including motility, growth, survival, and differentiation. Regions of cell-cell adhesion are adherens junctions, desmosomes, and tight junctions.
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The adhesion of cells to neighbor cells determines cellular and tissue morphogenesis and regulates major cellular processes including motility, growth, survival, and differentiation. Regions of cell-cell adhesion are adherens junctions, desmosomes, and tight junctions.
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Research in Veterinary Science, 2020
Mammary tumors represent the second most common neoplasia in the canine species, where more than 50% of the cases are classified as malignant. The histological classification is used as a prognostic tool. Cadherins and catenins are responsible for cell adhesion and are intrinsic connected with the process of metastasis.
Aline Alvarenga, da Rocha +2 more
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Mammary tumors represent the second most common neoplasia in the canine species, where more than 50% of the cases are classified as malignant. The histological classification is used as a prognostic tool. Cadherins and catenins are responsible for cell adhesion and are intrinsic connected with the process of metastasis.
Aline Alvarenga, da Rocha +2 more
openaire +2 more sources
Developmental Brain Research, 2005
Although cadherins and catenins are known to play important roles during neural development, the types of alpha-catenin present in the developing telencephalon are still unknown. Here, we show that the ventricular zones (VZ) of the cortex and the ganglionic eminences express alphaE-catenin and alphaN-catenin, respectively, in a complementary manner. In
Itsuki, Ajioka, Kazunori, Nakajima
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Although cadherins and catenins are known to play important roles during neural development, the types of alpha-catenin present in the developing telencephalon are still unknown. Here, we show that the ventricular zones (VZ) of the cortex and the ganglionic eminences express alphaE-catenin and alphaN-catenin, respectively, in a complementary manner. In
Itsuki, Ajioka, Kazunori, Nakajima
openaire +2 more sources
1999
Abstract Originally a-catenin was identified in immunoprecipitation experiments as a 102 kDa protein coprecipitating with antibodies against E-cadherin. Primary structure analysis of α-catenin revealed homology to vinculin, a protein first described as a component of focal adhesions, and suggested the existence of a vinculin-related ...
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Abstract Originally a-catenin was identified in immunoprecipitation experiments as a 102 kDa protein coprecipitating with antibodies against E-cadherin. Primary structure analysis of α-catenin revealed homology to vinculin, a protein first described as a component of focal adhesions, and suggested the existence of a vinculin-related ...
openaire +1 more source
Expression of Catenins during Mouse Embryonic Development and in Adult Tissues
Cell Adhesion and Communication, 1995Lionel Larue
exaly