Results 231 to 240 of about 10,852 (292)

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

open access: yesIbrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon   +5 more
wiley   +1 more source

Adherens junction protein expression is associated with poor response to neoadjuvant FLOT chemotherapy and pro‐inflammatory tumor microenvironment in esophageal adenocarcinoma

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Esophageal adenocarcinoma (EAC) is an aggressive cancer with poor survival and variable response to perioperative chemotherapy. Although histopathological features correlate with outcomes, the relationship specifically between adherens junction (AJ) protein expression and treatment response in EAC remains uncertain.
Bastian Grothey   +8 more
wiley   +1 more source

S100A11 is involved in the progression of colorectal cancer through the desmosome-catenin-TCF signaling pathway. [PDF]

open access: yesIn Vitro Cell Dev Biol Anim
Zhou J   +7 more
europepmc   +1 more source

Diagnostic accuracy of phosphatase and tensin homolog loss in differentiating between atypical endometrial hyperplasia/endometrioid intraepithelial neoplasia and non‐atypical endometrial hyperplasia: A systematic review and meta‐analysis

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Accurate distinction between atypical endometrial hyperplasia/endometrioid intraepithelial neoplasia (AH/EIN) and non‐atypical endometrial hyperplasia (EH) determines whether patients require hysterectomy or can be managed conservatively.
Kristina Shcherbatiuk   +6 more
wiley   +1 more source

The importance of gene polymorphism in familial inheritance of endometriosis

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The study aimed to investigate familial transmission patterns in women with endometriosis by generating a customized single‐nucleotide polymorphism (SNP) array. Methods Patients aged 18–45 who were diagnosed histopathologically with endometriosis were included in the study.
Hale Goksever Celik   +4 more
wiley   +1 more source

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