Results 21 to 30 of about 17,890 (223)

Report on Vincristine-Producing Endophytic Fungus Nigrospora zimmermanii from Leaves of Catharanthus roseus

Metabolites, 2022
Vincristine is an anti-cancer compound and one of the most crucial vinca alkaloids produced by the medicinal plant Catharanthus roseus (L.) G. Don. (Apocynaceae). This plant is home to hundreds of endophytic microbes, which produce a variety of bioactive
Kanchan Birat, Reem Binsuwaidan, Tariq Omar Siddiqi, Showkat Rasool Mir, Nawaf Alshammari, Mohd Adnan, Rahila Nazir, Bushra Ejaz, Moien Qadir Malik, Rikeshwer Prasad Dewangan, Syed Amir Ashraf, Bibhu Prasad Panda   +11 more
doaj   +1 more source

Identification and Assessment of Therapeutic Phytoconstituents of Catharanthus roseus through GC-MS Analysis

Separations, 2023
The leaves of Catharanthus roseus (L.) G. Don contain a large number of diverse secondary metabolites, making them comparably complex. The Catharanthus genus has received increased interest from scientists in recent years due to its extensive ...
Jyoti Rani, Manish Kapoor, Sanju Bala Dhull, Gulden Goksen, Slaven Jurić   +4 more
doaj   +1 more source

Exploration of the Mechanisms of Differential Indole Alkaloid Biosynthesis in Dedifferentiated and Cambial Meristematic Cells of Catharanthus roseus Using Transcriptome Sequencing

Frontiers in Genetics, 2022
Catharanthus roseus produces terpenoid indole alkaloids (TIAs) of high medicinal importance. The current research focuses on finding an efficient production system such as cell suspension cultures for high TIA concentrations.
Pengfei Zhou, Mingxiang Chen
doaj   +1 more source

The ORCA2 transcription factor plays a key role in regulation of the terpenoid indole alkaloid pathway [PDF]

, 2013
Background: The terpenoid indole alkaloid (TIA) pathway leads to the production of pharmaceutically important drugs, such as the anticancer compounds vinblastine and vincristine.
Gibson, Susan, Leopold, Alex, Li, Chun, Sander, Guy, Shanks, Jacqueline, Shanks, Jacqueline, Zhao, Le   +6 more
core   +3 more sources

Strictosidine activation in Apocynaceae: towards a "nuclear time bomb"? [PDF]

, 2010
Background The first two enzymatic steps of monoterpene indole alkaloid (MIA) biosynthetic pathway are catalysed by strictosidine synthase (STR) that condensates tryptamine and secologanin to form strictosidine and by strictosidine β-D-glucosidase (SGD ...
Guirimand Grégory, Courdavault Vincent, Lanoue Arnaud, Mahroug Samira, Guihur Anthony, Blanc Nathalie, Giglioli-Guivarc'h Nathalie, St-Pierre Benoit, Burlat Vincent   +8 more
core   +1 more source

GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway [PDF]

, 2016
Steroidal glycoalkaloids (SGAs) are cholesterol-derived molecules produced by solanaceous species. They contribute to pathogen defence but are toxic to humans and considered as anti-nutritional compounds.
Aharoni, Asaph, Burdman, Saul, Cárdenas, Pablo D, Dewangan, Veena, Giri, Ashok P, Goossens, Alain, Malitsky, Sergey, Meir, Sagit, Pollier, Jacob, Rogachev, Ilana, Sonawane, Prashant D, Tal, Lior, Vanden Bossche, Robin, Weithorn, Efrat   +13 more
core   +1 more source

Evaluation of the Nutritive and Organoleptic Values of Food Products Developed by Incorporated Catharanthus roseus (Sadabahar) Fresh Leaves Explore Their Hypoglycemic Potential

The Scientific World Journal, 2014
Diabetes becomes a real problem of public health in developing countries, where its prevalence is increasing steadily. Diabetes mellitus can be found in almost every population in the world. Since the Ayurvedic practice started in India, plants are being
Gita Bisla, Shailza Choudhary, Vijeta Chaudhary   +2 more
doaj   +1 more source

Study on the antioxidant potential of Catharanthus species and its thermal stability in sunflower oil model system

Cogent Food & Agriculture
The studies analyze the efficiency of Catharanthus alba and Catharanthus roseus cultivars as a natural antioxidant measuring antioxidant potential through two methods.
Yogesh Kumar Awasthi, RenuB. Sharma, Sarvesh Rustagi, Arti Thakur, Mehak Katyal, Sheetal Thakur, Kanika Dulta, Junaid Aman, Sumira Malik, Petr Slama   +9 more
doaj   +1 more source

Characterization of a new potyvirus causing mosaic and flower variegation in Catharanthus roseus in Brazil

Scientia Agricola, 2011
Catharanthus roseus is a perennial, evergreen herb in the family Apocynaceae, which is used as ornamental and for popular medicine to treat a wide assortment of human diseases.
Sheila Conceição Maciel, Ricardo Ferreira da Silva, Marcelo Silva Reis, Adriana Salomão Jadão, Daniel Dias Rosa, José Segundo Giampan, Elliot Watanabe Kitajima, Jorge Alberto Marques Rezende, Luis Eduardo Camargo   +8 more
doaj   +1 more source

Discovery of a Plant Pictet–Spenglerase With R‐Stereoselectivity

Angewandte Chemie, Volume 138, Issue 20, 11 May 2026.
Strictosidine synthases (STRs) are plant Pictet–Spenglerases catalyzing the coupling of a secoiridoid with tryptamine. All previously characterized strictosidine synthases are strictly S‐selective. Here, we report the discovery of Epi‐STR, an R‐selective STR ortholog from the medicinal plant Pogonopus speciosus.
Clara Morweiser, Sarah Heinicke, Sarah E. O'Connor, Maite Colinas   +3 more
wiley   +2 more sources