Results 41 to 50 of about 5,611 (178)

Harnessing benzamides as plant stress inhibitors, growth promoters and in management of crop resilience—A review

Plant Biology, EarlyView.
Benzamides boost crop resilience by inhibiting poly(ADP‐ribose) polymerase (PARP) to enhance stress tolerance and, through their antimicrobial, herbicidal, and insecticidal derivatives, they offer broad protection for sustainable crop improvement. Abstract Benzamides have emerged as potent stress inhibitors and growth promoters in plant biotechnology ...
M. J. Koetle, T. E. Motaung, S. O. Amoo
wiley   +1 more source

Topical Catharanthus roseus gel modulates TNF-α expression and SOD activity in UVB-induced skin: an in vivo experimental study

Medisains
Background: Subchronic UVB exposure induces oxidative stress and skin inflammation, characterized by increased TNF-α expression and decreased antioxidant activity, including superoxide dismutase (SOD).
Gina Noviana Gunawan, Setyo Trisnadi, Hadi Sarosa   +2 more
doaj   +1 more source

A Catharanthus roseus Fe(II)/α-ketoglutarate-dependent dioxygenase catalyzes a redox-neutral reaction responsible for vindolinine biosynthesis

Nature Communications, 2022
Catharanthus roseus is the source for anticancer drug vinblastine and other medicinal monoterpenoid indole alkaloids. Here the authors characterize an Fe/2OG dioxygenase, vindolinine synthase, which catalyzes an unusual redox-neutral reaction leading to ...
Jasmine Ga May Eng, Mohammadamin Shahsavarani, Daniel Patrick Smith, Josef Hájíček, Vincenzo De Luca, Yang Qu   +5 more
doaj   +1 more source

Systematic prioritization of candidate genes in camptothecin biosynthesis using multi‐omics and deep learning

The Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Camptothecin (CPT), a plant‐derived monoterpene indole alkaloid first identified in Camptotheca acuminata, is a drug precursor widely used for cancer chemotherapeutics. However, the full set of genes responsible for CPT biosynthesis remains unclear, hindering efforts to elucidate the complete pathway or establish biosynthetic production of CPT
Shenqi Wang, Xing Wu, Maria Moreno, Joonseok Oh, Stephen L. Dellaporta, Jason M. Crawford, Farren J. Isaacs   +6 more
wiley   +1 more source

Chitosan‐induced modulation of secondary metabolism and stress tolerance in Salvia rosmarinus under combined drought and heat stress

Journal of the Science of Food and Agriculture, Volume 106, Issue 10, Page 5989-6001, 15 August 2026.
Abstract BACKGROUND Abiotic stresses, particularly drought and elevated temperatures, negatively affect plant physiological and metabolic processes. This study investigated the effects of drought, heat, and combined stress on Salvia rosmarinus (rosemary), and evaluated foliar‐applied chitosan as a biostimulant.
Inês Mansinhos, Sandra Gonçalves, Raquel Rodríguez‐Solana, Efrén Pérez‐Santín, María I Fernández‐Marín, Emma Cantos‐Villar, Anabela Romano   +6 more
wiley   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, Volume 13, Issue 46, 17 August 2026.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Plant‐Derived Nanoparticles (PDNPs) in Food Safety and Preservation: Pros and Cons

eFood, Volume 7, Issue 4, August 2026.
Plant‐derived nanoparticles (PDNPs) synthesized via green methods demonstrate antimicrobial, antioxidant, barrier, eco‐friendly, and cost‐effective properties, while facing challenges in large‐scale production, synthesis standardization, and absence of specific food safety regulations. ABSTRACT Ensuring food safety and extending shelf life across fresh
Md. Shakil Ahmed, M. Mahadi Hasan, Most. Zakia Yeasmin   +2 more
wiley   +1 more source

A chromosome-level Camptotheca acuminata genome assembly provides insights into the evolutionary origin of camptothecin biosynthesis

Nature Communications, 2021
Camptothecin is a monoterpene indole alkaloid with anti-tumor activity. Here, the authors assemble the genome of the camptothecin producing plant Camptotheca acuminata and provide insights into the evolutionary origin of camptothecin biosynthesis by ...
Minghui Kang, Rao Fu, Pingyu Zhang, Shangling Lou, Xuchen Yang, Yang Chen, Tao Ma, Yang Zhang, Zhenxiang Xi, Jianquan Liu   +9 more
doaj   +1 more source

Cross‐stage single‐cell and spatial metabolome analyses reveal periderm specialization and tanshinone biosynthesis in Salvia miltiorrhiza roots

New Phytologist, Volume 251, Issue 3, Page 1267-1282, August 2026.
Biosynthesis and accumulation of tanshinones in the periderm of Salvia miltiorrhiza during secondary root growth. Summary Perennial herbs develop long‐lived roots that undergo repeated cycles of secondary growth, during which the periderm functions as a protective barrier and a major site of specialized metabolite accumulation.
Licheng Liu, Lianchong Gao, Zhi‐Ying Wang, Yan Liu, Huifeng Ju, Huana Lin, Zheng Shi, Wen‐Juan Cai, Xue Li, Yan‐Bo Huang, Yu Kong, Jing‐Jing Xu, Hong‐Peng Chen, Xin Fang, Juan Guo, Yong‐Hong Hu, Ke Chen, Xiao‐Ya Chen, Jie Hao, Lei Yang   +19 more
wiley   +1 more source

Monoterpenoid Indole Alkaloids from Cultivated in Yunnan

Natural Product Communications, 2015
A new monoterpenoid indole alkaloid, 15,20-dehydro-3α-(2-oxopropyl) coronaridine (1) , along with sixteen analogues (2–17) were isolated from the leaves of Catharanthus roseus cultivated in Yunnan.
Bei Wang, Lu Liu, Ying-Ying Chen, Qiong Li, Dan Li, Ya-Ping Liu, Xiao-Dong Luo   +6 more
doaj   +1 more source