AP2/ERF transcription factors regulate the biosynthesis of terpenoids, phenolics, and alkaloids in plants. [PDF]
Chen Q, Li N, Cui X, Ge F.
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Identification of DELLA and GID1 genes in Catharanthus roseus and their potential role in regulating vindoline biosynthesis. [PDF]
Cole-Osborn LF +5 more
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Influence of light type, cadmium, and glycine concentration on vinblastine and vincristine production in Catharanthus roseus cell suspension culture with response surface methodology-based optimization of elicitor condition. [PDF]
Tahami SK +3 more
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Unlocking the therapeutic potential of Catharanthus roseus leaves via in-vitro, in-vivo, and in-silico study. [PDF]
Sarkar BK +7 more
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Protective Role of Methanol Leaf Extract of Catharanthus Roseus in Lipid Profile Modulation in Diabetic Wistar Rats. [PDF]
Mallikarjuna Rao B +3 more
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Integrated metabolomics and transcriptomics investigate the bulb-specific biosynthesis of medicinal steroidal alkaloids in Fritillaria taipaiensis. [PDF]
Guo J +10 more
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Mining the Hidden Pharmacopeia: Fungal Endophytes, Natural Products, and the Rise of AI-Driven Drug Discovery. [PDF]
Al Shami R, Mousa WK.
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Biosynthetic pathway of terpenoid indole alkaloids in Catharanthus roseus
Frontiers of Medicine, 2014Catharanthus roseus is one of the most extensively investigated medicinal plants, which can produce more than 130 alkaloids, including the powerful antitumor drugs vinblastine and vincristine. Here we review the recent advances in the biosynthetic pathway of terpenoid indole alkaloids (TIAs) in C.
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