Results 171 to 180 of about 6,749 (214)

Alkaloid Production in Catharanthus roseus Cell Cultures VIII

Planta Medica, 1981
A cell line of Catharanthus roseus (L.) G. Don coded PRL # 200, was characterized with respect to its biosynthetic capabilities for indolealkaloids, in particular catharanthine, in suspension cultures. Other alkaloids isolated are vallesiachotamine isomers, ajmalicine, hörhammericine, hörhammerinine, vindolinine, 19-epivindolinine and strictosidine ...
W G, Kurz, K B, Chatson, F, Constabel, J P, Kutney, L S, Choi, P, Kolodziejczyk, S K, Sleigh, K L, Stuart, B R, Worth   +8 more
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Alkaloid catabolism and mobilization in catharanthus roseus

Phytochemistry, 1976
Abstract The catabolic turnover of vindoline and catharanthine, indole-dihydroindole alkaloids produced by Catharanthus roseus , occurs much more rapidly in apical cuttings than in intact plants. The implication of the results is that such alkaloids may participate actively in the plant's biochemical processes under certain conditions, in ...
Peter E. Daddona, James L. Wright, C.Richard Hutchinson   +2 more
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Analysis of Catharanthus roseus alkaloids by HPLC

Phytochemistry Reviews, 2007
Catharanthus roseus is a medicinal plant from which secondary metabolites used in chemotherapy to treat diverse cancers are extracted. The well known high value metabolites vincristine and vinblastine are just 2 of 130 alkaloids that can be found in C. roseus.
Steve Hisiger, Mario Jolicoeur
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Three New Terpenoid Indole Alkaloids fromCatharanthus roseus

Planta Medica, 2010
Three new terpenoid indole alkaloids, vidolicine (1), normacusine B N-oxide (2), and lochnerine N-oxide (3), together with seven known ones (4-10), were isolated from whole plants of Catharanthus roseus. Their structures were elucidated by spectroscopic methods (NMR, MS, UV, and IR).
Lei, Wang, Yu, Zhang, Hong-Ping, He, Qiang, Zhang, Shi-Fei, Li, Xiao-Jiang, Hao   +5 more
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Alkaloid production by transformed root cultures of Catharanthus roseus

Plant Cell Reports, 1988
Transformed roots of Catharanthus roseus were obtained following infection of detached leaves with Agrobacterium rhizogenes. Roots would not grow in full strength Gamborg's B5 medium but would grow satisfactorily if the medium was diluted to one half strength. Little alkaloid appeared in the growth medium but root tissue contained a high level and wide
A J, Parr, A C, Peerless, J D, Hamill, N J, Walton, R J, Robins, M J, Rhodes   +5 more
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Elicitors Enhance Alkaloid Yield in Catharanthus roseus

2017
Catharanthus roseus (L.) G. Don is an important plant of medicinal importance. A number of active compounds of this plant are anti-cancerous in nature. Two such compounds are vinblastine and vincristine; unfortunately, the level of these phytocompounds is very low.
Dipti Tonk, A. Mujib, Muzamil Ali, Nadia Zafar   +3 more
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Indole Alkaloids from the Roots of Catharanthus roseus

Chemistry of Natural Compounds, 2014
Catharanthus roseus (L.) G. Don is a well-known traditional herbal medicine, which is rich in indole alkaloids [1]. The chemical constituents of C. roseus have been investigated in our group [2, 3], and our further research has led to nine indole alkaloids (1–9) from the roots of C. roseus.
Chun-Hua Wang, Yu Zhang, Miao-Miao Jiang
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Two Pairs of Epimeric Indole Alkaloids fromCatharanthus roseus

Planta Medica, 2011
Two pairs of epimeric indole alkaloids (1- 4) with a chlorine atom were isolated from the aerial part of Catharanthus roseus. Their structures were established on the basis of the spectroscopic data including UV, IR, HRESIMS, NMR, and X-ray diffraction analyses. The cytotoxic activities of 1-4 against the HepG2 cell line were evaluated.
Guo-Cai, Wang, Xiang-Zhan, Zhong, Dong-Mei, Zhang, Ying, Wang, Xiao-Qi, Zhang, Ren-Wang, Jiang, Yao-Lan, Li, Jiao, Wang, Xin-Sheng, Yao, Wen-Cai, Ye   +9 more
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Vincazalidine A, a unique bisindole alkaloid from Catharanthus roseus

Journal of Natural Medicines
A new dimeric indole alkaloid, vincazalidine A consisting of an aspidosperma type and a modified iboga type with 1-azatricyclo ring system consisting of one azepane and two piperidine rings coupled with an oxazolidine ring was isolated from Catharanthus roseus, and the structure including absolute stereochemistry was elucidated on the basis of ...
Yusuke, Hirasawa, Ayaka, Kase, Akie, Okamoto, Keigo, Suzuki, Mizuki, Hiroki, Toshio, Kaneda, Nahoko, Uchiyama, Hiroshi, Morita   +7 more
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The iridoid pathway in Catharanthus roseus alkaloid biosynthesis

Phytochemistry Reviews, 2007
The Apocynaceae Catharanthus roseus accumulates a number of monoterpene indole alkaloids (MIAs) that originate from the coupling of the indole and the iridoid pathways. The latter pathway is usually considered as limiting for MIA biosynthesis, but evidence is now strong that the precursors tryptamine (from the indole pathway) and secologanin (from the ...
Audrey Oudin, Martine Courtois, Marc Rideau, Marc Clastre   +3 more
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