Detection of Cathelicidin-1 and Cathelicidin-2 Biomolecules in the Milk of Goats and Their Use as Biomarkers for the Diagnosis of Mastitis [PDF]
AnimalsThe objectives of the present work were as follows: (i) the detection of cathelicidin biomolecules in the milk of individual goats during the early stages of mastitis and their potential use for the diagnosis of mastitis at its early stage and (ii) the ...
Maria V. Bourganou +12 more
doaj +2 more sources
The neutrophil antimicrobial peptide cathelicidin promotes Th17 differentiation
Nature Communications, 2021 Neutrophils secrete numerous immune effector molecules including cathelicidin which is associated with antimicrobial properties. Here the authors implicate neutrophil derived cathelicidin in modulation of CD4 T cell homoeostasis and the promotion of Th17
Danielle Minns +2 more
exaly +2 more sources
Cathelicidin regulates goblet cell mucus secretion and mucus-associated proteins in Citrobacter rodentium-induced colitis [PDF]
Gut MicrobesColonic goblet cells play a crucial role in mucosal defense by secreting Muc2 mucin and other proteins that entrap and expel enteropathogens. However, the role of innate effectors in the gut like cathelicidin peptides in regulating the mucus barrier ...
Niloofar Mirzadzare +12 more
doaj +2 more sources
Cathelicidin in Urinary Tract Diseases: Diagnostic, Prognostic and Therapeutic Potential of an Evolutionary Conserved Antimicrobial Protein [PDF]
MedicinaDespite being one of the most common infectious diseases, urinary tract infections (UTIs) still represent a challenge for clinicians to diagnose and treat, especially in the era of growing antibiotic resistance among uropathogenic bacteria.
Iva Sorić Hosman +7 more
doaj +2 more sources
PLoS ONE, 2011 The extensive world-wide morbidity and mortality caused by influenza A viruses highlights the need for new insights into the host immune response and novel treatment approaches. Cationic Host Defense Peptides (CHDP, also known as antimicrobial peptides),
Peter G Barlow, Ian A York, Jan Pohl
exaly +3 more sources
Cathelicidin: Insights into Its Impact on Metabolic Syndrome and Chronic Inflammation [PDF]
MetabolitesBackground/Objectives: LL-37 is associated with metabolic syndrome (MetS), a constellation of risk factors comprising obesity, insulin resistance (IR), dyslipidemia, and hypertension, which elevates the risk of cardiovascular disease and type 2 diabetes.
Alina Delia Popa +6 more
doaj +2 more sources
International Journal of Mycobacteriology, 2023 Background: The immunomodulatory effects of Vitamin D expand to induce the synthesis of an antimicrobial peptide, cathelicidin. There is evidence showing altered levels of cathelicidin in tuberculosis (TB).
Yuvaraj Balan +4 more
doaj +1 more source
The antimicrobial peptide cathelicidin protects mice from Escherichia coli O157:H7-mediated disease. [PDF]
PLoS ONE, 2012 This study investigated the role of the antimicrobial peptide cathelicidin in Escherichia coli O157:H7 infection and subsequent renal damage. Mouse and human cathelicidin, CRAMP and LL-37, respectively, killed E. coli O157:H7 in vitro.
Milan Chromek +2 more
doaj +1 more source
The frog skin-derived antimicrobial peptide esculentin-1a(1-21)nh2 promotes the migration of human hacat keratinocytes in an egf receptor-dependent manner: a novel promoter of human skin wound healing? [PDF]
, 2015 One of the many functions of skin is to protect the organism against a wide range of pathogens. Antimicrobial peptides (AMPs) produced by the skin epithelium provide an effective chemical shield against microbial pathogens. However, whereas antibacterial/
Cappiello, Floriana +6 more
core +10 more sources
Snake cathelicidin from Bungarus fasciatus is a potent peptide antibiotics. [PDF]
PLoS ONE, 2008 BACKGROUND: Cathelicidins are a family of antimicrobial peptides acting as multifunctional effector molecules of innate immunity, which are firstly found in mammalians. Recently, several cathelicidins have also been found from chickens and fishes.
Yipeng Wang +8 more
doaj +1 more source