Results 91 to 100 of about 24,668 (220)

The potential for immunoglobulins and host defense peptides (HDPs) to reduce the use of antibiotics in animal production [PDF]

, 2018
Innate defense mechanisms are aimed at quickly containing and removing infectious microorganisms and involve local stromal and immune cell activation, neutrophil recruitment and activation and the induction of host defense peptides (defensins and ...
A Al-Mamun, A Calmette, A Dijk van, A Dijk van, A Gronberg, A Kalita, A Lihme, A Nijnik, AH Achtman, AL Hilchie, Albert van Dijk, AM Does van der, AS Ferreira, B Rivas-Santiago, BA Blok, BS Graham, C Subbalakshmi, CD Fjell, Chris J. Hedegaard, CJ Hedegaard, CJ Hedegaard, CJ Hedegaard, CSF Bah, D Carlander, D Torrallardona, D Yang, D Yang, DA O’Neil, DA O’Neil, DC Speksnijder, DJ Davidson, DM Bowdish, DM Weaver, E Miraglia, E Tourneur, F Nimmerjahn, G Marano, G Vidarsson, H Liu, H Sherman, Henk P. Haagsman, I Nagaoka, J Kindrachuk, J Kleinnijenhuis, J Kovacs-Nolan, J Kovacs-Nolan, J Kovacs-Nolan, J Rohrl, J Schauber, JB Schaal, JD Heilborn, JH Es van, JL Pierce, K Chakraborty, K Chakraborty, K Moor, K Putsep, L Bandholtz, L Kannan, L Steinstraesser, L Zhang, LT Sunkara, M Akdis, M Cappelletti, M Coorens, M Coorens, M Ohno, M Ren, M Schlee, M Schlee, M Schwab, MA Hamon, MA Keller, MD Kraaij, MG Netea, MJ Alam, MM Rahman, N Mookherjee, N Mookherjee, NH Salzman, NY Yount, OE Sorensen, P Fehlbaum, P Presicce, P Sarker, P Tewary, Peter M. H. Heegaard, R Fisher, R Nocerino, R Ramos, R Raqib, RA Dorschner, RE Hancock, RE Hancock, RE Hancock, RI Lehrer, RJ Arts, RL Gallo, RL Hassfurther, RP Darveau, RS Rekha, S Caro Di, S Godden, S Saeed, SH Kim, T Cuperus, T Cuperus, TA Pham, TJ Newby, U Gerstel, V Petrov, V Virdi, VA Schneider, VK Lishko, W Jiang, WL Hurley, X Qiu, X Zeng, Y Goto   +118 more
core   +2 more sources

Prognostic Significance of the Pretreatment Neutrophil‐to‐Lymphocyte Ratio and Tumor‐Associated Neutrophils in Head and Neck Squamous Cell Carcinoma: Systematic Review and Meta‐Analysis

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Objectives The prognostic significance of the neutrophil‐to‐lymphocyte ratio (NLR) and tumor‐associated neutrophils (TANs) in head and neck squamous cell carcinoma (HNSCC) remains a subject of considerable research interest. This systematic review and meta‐analysis aimed to evaluate the relationship between pretreatment NLR and TANs and ...
Ahana Kapuge Dona Varuni Yashodha Ratnayake, Aini Hyytiäinen, Georgia Vasiliki Gkountana, Meri Torri, Ahmed Al‐Samadi   +4 more
wiley   +1 more source

Host Cathelicidin Exacerbates Group B Streptococcus Urinary Tract Infection

mSphere, 2020
Group B Streptococcus (GBS) causes frequent urinary tract infection (UTI) in susceptible populations, including individuals with type 2 diabetes and pregnant women; however, specific host factors responsible for increased GBS susceptibility in these ...
Kathryn A. Patras, Alison Coady, Priyanka Babu, Samuel R. Shing, Albert D. Ha, Emma Rooholfada, Stephanie L. Brandt, Matthew Geriak, Richard L. Gallo, Victor Nizet   +9 more
doaj   +1 more source

LL-37 boosts immunosuppressive function of placenta-derived mesenchymal stromal cells [PDF]

, 2016
Background: Although promising for graft-versus-host disease (GvHD) treatment, MSC therapy still faces important challenges. For instance, increasing MSC migratory capacity as well as potentializing immune response suppression are of interest.
Araujo, Felipe Saldanha de, Bravo, Martha Oliveira, Carvalho, Juliana Lott, Covas, Dimas Tadeu, Franco, Octávio Luiz, Neves, Francisco de Assis Rocha, Panepucci, Rodrigo Alexandre, Pereira, Rinaldo Wellerson, Sangiorgi, Bruno Braga, Schiavinato, Josiane Lilian dos Santos   +9 more
core   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Natural Antimicrobial Peptides: Pleiotropic Molecules in Host Defense [PDF]

, 2013
Natural antimicrobial peptides (AMPs) are small cationic molecules that display antimicrobial activity against a wide range of bacteria, fungi and viruses.
Maffia, Paulo Cesar, Martínez, Melina María Belén, Sanchez, Mercedes Leonor   +2 more
core   +1 more source

Bactericidal Activity of Mammalian Cathelicidin-Derived Peptides [PDF]

Infection and Immunity, 2000
ABSTRACT Endogenous antimicrobial peptides of the cathelicidin family contribute to innate immunity. The emergence of widespread antibiotic resistance in many commonly encountered bacteria requires the search for new bactericidal agents with therapeutic potential. Solid-phase synthesis was employed to prepare linear antimicrobial
S M, Travis, N N, Anderson, W R, Forsyth, C, Espiritu, B D, Conway, E P, Greenberg, P B, McCray, R I, Lehrer, M J, Welsh, B F, Tack   +9 more
openaire   +2 more sources

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Escherichia coli expression and purification of LL37 fused to a family III carbohydrate-binding module from Clostridium thermocellum [PDF]

, 2010
The cathelicidin derived human peptide LL37 has a broad spectrum of antimicrobial and immunomodulatory activities. The large variety of biological activities makes LL37 a very promising candidate for clinical applications.
Domingues, Lucília, Gama, F. M., Ramos, Reinaldo Rodrigues   +2 more
core   +1 more source

Cathelicidins in the Tasmanian devil (Sarcophilus harrisii) [PDF]

Scientific Reports, 2016
AbstractTasmanian devil joeys, like other marsupials, are born at a very early stage of development, prior to the development of their adaptive immune system, yet survive in a pathogen-laden pouch and burrow. Antimicrobial peptides, called cathelicidins, which provide innate immune protection during early life, are expressed in the pouch lining, skin ...
Peel, E., Cheng, Y., Djordjevic, J. T., Fox, S., Sorrell, T. C., Belov, K.   +5 more
openaire   +3 more sources