Results 101 to 110 of about 52,950,106 (199)

Cancer cell migration under control of human cathelicidin LL-37

Biomedicine & Pharmacotherapy
Cancer cell migration is a key step in the metastatic cascade. Understanding its mechanisms represents one of the greatest challenges in modern oncology. Both in vitro and in vivo experimental models and mathematical descriptions of movement dynamics are used to study this complex phenomenon.
Żochowski, Konrad, Sadowska, Maja, Ewelina Piktel, Pogoda, Katarzyna, Robert Bucki   +4 more
openaire   +2 more sources

No evidence of pathogenic involvement of cathelicidins in patient cohorts and mouse models of lupus and arthritis.

PLoS ONE, 2014
Apart from their role in the immune defence against pathogens evidence of a role of antimicrobial peptides (AMPs) in autoimmune diseases has accumulated in the past years.
D Kienhöfer, J Hahn, I Schubert, C Reinwald, N Ipseiz, S C Lang, È Bosch Borràs, K Amann, C Sjöwall, A E Barron, A J Hueber, B Agerberth, G Schett, M H Hoffmann   +13 more
doaj   +1 more source

Antimicrobial Peptides of the Cathelicidin Family: Focus on LL-37 and Its Modifications

International Journal of Molecular Sciences
Cathelicidins are a family of antimicrobial peptides (AMPs) with broad-spectrum activity and immunomodulatory functions. Among them, the only human cathelicidin LL-37 has garnered significant interest due to its potent antimicrobial, antiviral, antifungal, antiparasitic, and antitumor properties.
Olga Evgenevna Voronko, Victoria Alexandrovna Khotina, Dmitry Alexandrovich Kashirskikh, Arthur Anatolievich Lee, Vagif Ali oglu Gasanov   +4 more
openaire   +3 more sources

Cathelicidin LL-37: LPS-neutralizing, pleiotropic peptide.

Annals of agricultural and environmental medicine : AAEM, 2007
Human organism, constantly exposed to a large variety of pathogenic microorganisms and their products, such as lipopolysaccharide (LPS), developed innate immunity as a first line of defence. One of the compartments of our organism well equipped with these defence mechanisms is the respiratory system. The cells lining the airways respond to the presence
openaire   +2 more sources

Engineered Exosomes Containing Cathelicidin/LL-37 Exhibit Multiple Biological Functions. [PDF]

Adv Healthc Mater, 2022
Su Y, Sharma NS, John JV, Ganguli-Indra G, Indra AK, Gombart AF, Xie J.   +6 more
europepmc   +1 more source

Nafcillin Augmentation of Daptomycin and Cathelicidin LL-37 Killing of Methicillin-resistant Staphylococcus epidermidis: Foundations of Successful Therapy of Endocarditis. [PDF]

Int J Antimicrob Agents, 2023
Catteau L, Iglesias YD, Tsunemoto H, Pogliano J, Van Bambeke F, Nizet V, Sakoulas G.   +6 more
europepmc   +1 more source

Cathelicidin peptide LL-37: A multifunctional peptide involved in heart disease

Pharmacological Research
Heart disease is a common human disease with high morbidity and mortality. Timely and effective prevention and treatment is an urgent clinical problem. The pathogenesis of heart disease is complex and diverse, involving hypertension, diabetes, atherosclerosis, drug toxicity, thrombosis, infection and other aspects. LL-37, an endogenous peptide, is well
Shuo Miao, Houde Liu, Qingyu Yang, Yaping Zhang, Tao Chen, Shuai Chen, Xin Mao, Qingsong Zhang   +7 more
openaire   +3 more sources

Evaluation of LL 37 Lipoprotein As Innate Immunity Marker among Sudanese Patients Cutaneous Leishmania

Sudan Journal of Medical Sciences, 2019
Background: The leishmaniasis is a group of diseases with a broad range of clinical manifestations caused by several species of parasites belonging to the genus Leishmania.
Ayat H. Bakr, Abugroun E. A., AbdElkarim A. Abdrabo, Omeyma A. Mohamed, Mokhtar M. A., GadAllah Modawe   +5 more
doaj   +1 more source

Cathelicidin (LL-37) causes expression of inflammatory factors in coronary artery endothelial cells of Kawasaki disease by activating TLR4-NF-κB-NLRP3 signaling. [PDF]

Immun Inflamm Dis, 2023
Si F, Lu Y, Wen Y, Chen T, Zhang Y, Yang Y.   +5 more
europepmc   +1 more source

Design, synthesis, and characterization of non-hemolytic antimicrobial peptides related to human cathelicidin LL-37. [PDF]

RSC Adv, 2023
Krishnamoorthy R, Adhikari P, Anaikutti P.   +2 more
europepmc   +1 more source